摘要
在微波辐射下,以稀土固体超强酸SO42-/TiO2/La3+为催化剂合成氯乙酸异丙酯。考察微波输出功率、反应时间、催化剂用量、酸醇的物质的量比等因素对反应的影响。通过实验得出合成氯乙酸异丙酯的最佳反应条件是:氯乙酸和异丙醇的物质的量比为1∶2.5,催化剂用量为0.5g,微波输出功率为729W,反应时间为12min,在此反应条件下,氯乙酸的酯化率为95.6%。
Isopropyl chloroacetate is synthesized from chloroacetic acid and isopropyl alcohol with rare earth solids upper acid SO4^2-/ TiO2/ La^3＋ as catalysts under the irradiation of microwave. It is investigated that the effects of microwave irradiation power（P）, reaction time（T）, the amount of catalyst and molar ratio of acid-alcohol on the process. The optimum operation conditions are obtained by experiment and are as follows： the mole ratio of chloroacetic acid and isopropyl alcohol is 1：2.5 （mol / mol ）, the amount of catalyst is 0.5 g, irradiation power 729 W, reaction time 12 min. Under above conditions, 95.4% of chloroacetic acid is converted, the yield chloroacetates is 89.4%.
出处
《广东化工》
CAS
2006年第12期42-44,共3页
Guangdong Chemical Industry
作者简介
兰翠玲（1963-），女，广西大化人，副教授。主要研究方向为有机合成和配位化学。
