摘要
目的 探讨舒芬太尼麻醉用于心脏手术对血液动力学的影响。方法 随机选择40例择期冠脉搭桥或瓣膜置换手术患者，分为舒芬太尼组和芬太尼组，每组20例。分别在麻醉诱导前（T1）、插管后5min（T2）、转流前即刻（T3）、停机后即刻（T4）、停机后10min（T5）、关胸后（T6）、手术结束时（T7）记录HR、SBP、DBP、心输出量（CO）、每搏量（SV）、周身血管阻力（SVR）。结果两组患者HR在T3～T7时均显著高于T1时（P〈0．05），SBP、DBP均低于T1时，SVR在T6～T7时较T3时有所降低，而两组间各时点血液动力学指标差异均无显著意义。结论舒芬太尼麻醉与等效剂量芬太尼麻醉一样可以安全的应用于心脏手术。
Objective To investigate the effects of sufentanil anesthesia on hemodynamic changes in the patients undergoing heart surgery. Methods Forty patients undergoing elective CABG or valve replacements were randomly divided into sufentanil （S） group and fentanyl （F） group with 20 eases each. HR, SBP, DBP, CO, SVR, SV were recorded before anesthesia induction, at 5 min after trachea intubation,just before initiation of cardiopulmonary bypass（CPB）,just after discontinuing CPB, 10 min after discontinuing CPB,and after sternal closure. Results HR after discontinuing CPB was significantly higher and BP lower than those before anesthesia induction. SVR was significantly decreased after discontinuing CPB than that before initiation of CPB. There was no any significant difference in the hemodynamics at the same time points between two groups. Conclusion Sufentanil or equivalent dose fentanyl anesthesia can be safely used in patients undergoing heart surgery.
出处
《临床麻醉学杂志》
CAS
CSCD
2006年第11期816-817,共2页
Journal of Clinical Anesthesiology
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