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糖尿病周围神经病变治疗的循证医学证据 被引量:7

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摘要 糖尿病周围神经病变是糖尿病最常见的慢性并发症之一,发生率达50%~60%。其发生与糖尿病病程有关,并随着年龄增长其发生率将逐年升高。病因主要是长期严重的高血糖及由此而导致的代谢障碍、微循环异常和自身免疫紊乱。糖尿病周围神经病变临床表现多种多样,一般末梢神经首先受累,对称性多发性神经病变及自主神经病变较常见,而且常呈慢性进行性发展。该病早期的常见表现有肢体麻木、对称性下肢疼痛、刺痛甚至剧痛,部分患者可出现单肢周围神经或脊神经分布区域剧烈疼痛。糖尿病周围神经病变严重影响患者的生活质量,给患者带来巨大痛苦,但目前临床上尚缺乏特异性治疗方法。故以控制饮食、严格控制血糖水平作为预防和治疗的根本措施,同时辅以针对病因的治疗。
出处 《中国现代神经疾病杂志》 CAS 2006年第6期449-452,共4页 Chinese Journal of Contemporary Neurology and Neurosurgery
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参考文献21

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