摘要
目的：探讨胃肠道外间质瘤（EGIST）的临床病理特点和CT表现。方法：12例经手术病理证实的胃肠外间质瘤的患者均经CT平扫加增强扫描，回顾性分析其临床病理特点及影像学表现。结果：12例EGIST，腹膜后间隙4例，肠系腹5例，网膜3例。瘤体最大直径6～14cm，平均8cm。10例肿瘤呈圆形或卵圆形，2例呈分叶状。9倒边界清晰，3例边界不清。8例肿瘤可见囊变坏死，4例肿瘤内见出血。增强后12例呈明显不均性强化。6例伴有肝脏转移，3例伴有腹膜转移，未见腹水和转移性淋巴结肿大征象。组织病理检查，梭形细胞型8例。上皮样细胞型3例．混合型1例。免疫组化检查，所有病例CD117均表达阳性，7例CD34表达阳性。结论：临床上．EGIST很少出现消化道出血和梗阻症状，其病理特点与GIST相似，CT表现除肿瘤形态多呈圆形或卵圆形外，肿瘤大小、边缘、增强模式、转移和播散方式均类似于恶性GIST。
Objective：To investigate the clinico-pathological features and CT findings of extragastrointestinal stromal tumors （EGIST）. Methods： 12 cases of surgically and pathologically proven extragastrointestinal stromal tumors were included. Non-enhanced and enhanced CT were performed in all the patients. The clinical and pathological features as well as CT findings were reviewed retrospectively. Results： Tumors originated from the retroperitoneum in 4 cases,mesentery in 5 cases and omentum in 3 cases. The diameters of the masses ranged from 6cm to 14cm with an average of 8cm. Contours of the tumor were round or eval （n= 10） and lobulated （n=2）. Margins of the tumors were well-defined （n=9） and poorlydefined （n=3）.Cystic clanges and necroses with the tumors were found in 8 cases and intra-tumoral hemorrhage were seen in 4 cases. On enhanced CT,all of the tunmhowed heterogeneous enhancement. Metastases to the liver and to the peritoneum were found in 6 and 3 cases respectis： No ascites and metastatic lymphadenectasis were seen. Histio-pathologicaly,the types of tumors were classified as sprice cell tumors （n= 8）,epithelioid cell tumors （n=3） and mixture cell tumors （n= 1 ）. Positive expression of CD117 was detected in all cases and posit ivc expression of CD34 was demonstrated in 7 cases. Conclusion：Clinically, EGIST seldom presented the symptoms and signs of gasrointestinal hemorrhage and obstruction. The pathological features of EGIST were similar to those of GIST. Except the contour of the tumors （the majority of EGIST shaped as round or oval）, the GT signs of EGIST, including the tumor size, margins, contrast enhancement patterns, patterns of metastasis and spreeeding routes of the tumors simulated those of malignant GIST as well.
出处
《放射学实践》
2006年第11期1148-1151,共4页
Radiologic Practice
关键词
胃肠肿瘤
体层摄影术
X线计算机
Gastrointestinal neoplasms
Tomography,X-ray computed
作者简介
周智（1968-），女，江苏宜兴人，主治医师，主要从事肿瘤影像诊断工作.
