摘要
目的：研究蜂胶黄酮对小鼠脑组织的抗氧化系统的作用,以期探讨蜂胶黄酮的抗衰老作用机制。方法：以小鼠为实验对象,以其脑SOD、CSH-Px、MDA为指标,考察蜂胶黄嗣的抗衰老作用。结果：蜂胶乙醇提取物(EEP)可使脑组织中SOD、GSH- Px活性明显增高,和空白组相比具有显著差异(P＜0．01)；使脑组织MDA明显降低,和空白组相比具有显著差异(P＜0．01)。结论：EEP可有效地提高脑组织中抗氧化酶的活性,降低脑MDA的含量,抑制和／或减轻脂质过氧化反应,从而防止了自由基过氧化对脑组织的损伤,可能是有效的脑组织保护剂。
Objective： To investigate the effects and mechanism of propolis flavone in the mice＇s brains. Methods： Propohs flavone was given to mice for 25 days. Then the study ability of mice, the content of SOD, GSH - Px and MDA were determined. Results： The extract of propolis flavone, EEP, could increase the ability of SOD and GSH- Px in the brain tissue and decrease that ef MDA, compared with the control group, there were significant differences（P all 〈 0.01）. Conclusion： EEP can raise the activity of the anti - oxidized enzyme in tile brain tissue effectively, lower the content of MDA and inhibit and/or alleviate the over- oxidization reaction of lipin so as to avoid the damages of the brain tissue caused by the free radicals＇over- oxidization; therefore, it may be an effective protective drug for the brain tissue.
出处
《现代生物医学进展》
CAS
2006年第10期62-63,共2页
Progress in Modern Biomedicine
作者简介
张悦，（1965-），女，副教授，硕士研究生 主要研究方向：中西医结合抗衰老机制研究。
