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动态CT评估星形细胞瘤分级的前瞻性研究 被引量:4

A Prospective Study in Evaluating the Pathological Grading of Astrocytoma by Dynamic CT
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摘要 本文前瞻性的对32例星形细胞瘤患者做了动态CT扫描。结果显示:TBR_L值、HU_(L-F)值与星形细胞瘤的病理分级明显相关(P<0.01),代表肿瘤组织在5min末细胞外间隙剩余的碘,系血脑屏障破坏造成碘的回收障碍所致,肿瘤恶性程度越高,其对碘的廓清率越低。HU_P值及TBR_P值表示肿瘤的强化程度,与星形细胞瘤病理分级相关(P<0.05)。本文还给出了时间-密度曲线峰值后1min碘廓清率的计算公式,在本组病例中也显示有一定的差异性。本组指标对星形细胞瘤级别的判断总体敏感性为83.3%,特异性为86.7%,准确率为87.2%,与常规CT相比,动态CT扫描曲线参数分析可明显提高术前定性的特异性和准确性。 This article prospectively studied the dynamic CT(DCT ) findings in 32 cases of astrocytomas. The result showed: TBRL, HUL- F indicated the content of remained iodine in outspace of tumor cells at the end of 5 minutes. The rate of reabsorbed iodine was obstruced due to destruction of blood brain barrier. Along with the increase of pathological grading, the rate of clearing iodine decreased. This indices correlated with the pathological grading significantly (P<0. 01) . The HUP and TBRP represented the degree of enhancement of tumor and correlated with the pathological grading of astrocytoma (P<0.05) . In other ways, the author built a formula of the clearing rate of contrast medium one minute after peak. It was found that the diagnostic accuracy of astrocytoma by analysing the parameter of time-density curve was higher than that of the conventional CT before operation.
出处 《中国医学影像学杂志》 CSCD 1996年第3期137-139,共3页 Chinese Journal of Medical Imaging
关键词 星形细胞瘤 CT astrocytoma tomography X-ray computed analysis
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