摘要
以三乙胺为催化剂,维生素E和乙酸酐为原料合成维生素E乙酸酯,研究了反应原料配比、催化剂用量、反应时间、反应温度等因素对合成的影响。通过均匀设计方法确定最佳合成工艺:维生素E与乙酸酐的m ol比为1∶1.6,催化剂三乙胺用量为0.13 m l,温度55℃,反应时间5 h,反应转化率达95.4%.
Catalyzed by triethy lamine, vitamin E acetate was synthesized with vitamin E and acetic anhydride. The effects of reaction conditions such as molar ratio of vitamin E and acetic anhydride, the amount of catalyst, reaction time and temperature on the synthesis were studied. Uniform design was used to optimize the synthesis. The optimum conditions were determined as follows, the molar ratio of vitamin E and acetic anhydride was 1 ： 1. 6, the amount of catalyst was 0. 13ml, the reaction time was 5hr, and the reaction temperature was the 55℃, conversion of vitamin E acetic was 95.4%.
出处
《广西工学院学报》
CAS
2006年第3期33-35,40,共4页
Journal of Guangxi University of Technology
基金
广西教育厅科研项目资助(2003812)
关键词
维生素E乙酸酯
三乙胺
合成
Vitamin E acetate
Tiethy lamine
Synthesis
作者简介
郑燕升（1965-）,男,柳州市人,广西工学院副教授,广西大学在读研究生.
