摘要
Tw ist蛋白是属于碱性的螺旋-环-螺旋蛋白家族中的高度保守的转录因子,在胚胎的发生发展中发挥重要作用。Tw ist被认为是癌基因蛋白,影响肿瘤细胞的凋亡。Tw ist作为上皮-间质转变(ep ithelial-m esenchym altransition,EMT)过程中的关键调控因子,对肿瘤的侵袭和转移有重要影响。
The of basic helix-loop-helix as an oncogene protein, Twist protein is a highly conserved transcription factor that belongs to the family proteins, and it plays an important role in the embryogenesis. Twist is regulating regarded the apoptosis of tumor cells. It has been shown that Twist is a key regulator of epithelial-mesenchymal transition and responsible for the invasion and metastasis of tumor.
出处
《国际病理科学与临床杂志》
CAS
2006年第5期395-397,共3页
Journal of International Pathology and Clinical Medicine
作者简介
罗庚求（1973-），男，湖南邵阳人，博士研究生，讲师，主要从事消化道肿瘤病理研究。
