摘要
目的:了解恶性肿瘤住院患者抑郁的发生率,探讨其发生的相关因素,为在病房中开展恶性肿瘤患者抑郁的防治提供理论依据。方法:采用自评和访谈调查方法,应用Zung抑郁自评量表(SDS)、汉密尔顿抑郁量表(HAMD)、数字疼痛分级法(NRS)、一般状况评定量表以及有关恶性肿瘤患者疾病和社会信息的一般状况调查表进行调查。结果:407例恶性肿瘤住院患者有206例被诊断出抑郁,检出率为50·6%。单因素分析显示:性别、文化水平、既往化疗史、知情、慢性持续性疼痛、KPS评分、经济压力及社会支持的8项因素与抑郁发生显著相关(P<0·05)。经Logistic回归分析,性别、既往化疗史、知情、慢性持续性疼痛、KPS评分、社会支持6个自变量进入回归方程。结论:恶性肿瘤住院患者抑郁的发生率目前较高,对女性、既往有化疗史、知情、有慢性持续性疼痛、KPS评分低、社会支持不足者,应及早给予心理干预、必要的社会支持和治疗,以提高患者的治疗效果及改善生存质量。
Objective： To investigate the incidence of depression and its related factors in order to provide references for prevention and cure of depression of patients with malignant tumor in ward. Methods： 407 patients were enrolled. The methods include self - comment and investigation. The self- Rating Depression Scale （SDS）, the Hamilton Depression Scale （HAMD）, numerical rating scale （NRS）, the questionnaire of common condition were adopted and the information alout disease and conwnon society characteristic of patients were collected. All the data were analyzed by single factor χ^2 analysis, multinomial logistic regression methods. Results： Among 407 patients, 206 （50.6 % ） were detected as depression. Single factor analysis showed that gender, education degree, chemotherapy experience , being informed of the diagnosis, chronic persistent pain, KPS, economic status and social support were correlated with depression （P 〈 0.05） . With logistic regression analysis, gender, chemotherapy experience, being informed of the diagnosis, chronic persistent pain, KPS, social support were included in the equation. Conclusion： The incidence of depression in patients with malignant tumor is relatively high . In order to improve therapeutic effect and quality of life, early psychological intervention, some social support and therapy should be offered to those of female, chemotherapy experience, being informed of the diagnosis, existing chronic persistent pain, poor KPS, in.sufflcient social support.
出处
《现代预防医学》
CAS
北大核心
2006年第10期1841-1843,共3页
Modern Preventive Medicine
关键词
肿瘤
抑郁
相关因素
Malignant tumor
Depression
Related factors
作者简介
李力（1971～），女，硕士，主治医师．
[通讯作者]赵卫东，硕士，E-mail：zhao1120@yahoo．com．cn
