摘要
目的:提高临床对原发性小细胞肾癌的认识。方法:报告2例原发性小细胞肾癌的临床资料,结合文献对其临床特征和治疗方法进行归纳。结果:患者均以疼痛为主诉就诊,均无血尿病史;从出现症状到就诊的时间分别为1个月和2个月;肿瘤大小分别21cm和4.5cm,术前分期T4N1M0和T3N2M1;均行手术治疗,1例术后接受免疫治疗;术后生存时间分别为19个月和1个月。结论:原发性肾脏小细胞癌恶性程度较高,预后差;治疗上宜采取全身化疗为主的综合治疗,以延长患者生存时间。
Objective:To improve the diagnosis and treatment of primary small cell carcinoma of kidney. Methods:The clinical, pathological, therapeutic regimen and prognostic data of 2 cases with primary small ceil carcinoma of kidney were presented. Results: The main symptom of 2 cases was abdominal or flank pain without hematuria, the duration of symptoms was 1 month and 2 months, tumor size was 21cm and 4.5cm, staged pre-operafively as T4N1M0 and T3N2M1, one received immunotherapy after operation, the post operative survival was 19 months and 1 month, respectively. Conclusionsz Primary small cell carcinoma of kidney is an extremely rare neoplasm with aggressive behavior and poor prognosis. Combined therapeutic strategy, especially systemic chemotherapy should be taken to improve the survival of patients.
出处
《临床泌尿外科杂志》
2006年第10期732-734,共3页
Journal of Clinical Urology
关键词
肾脏肿瘤
综合治疗
原发性小细胞肾癌
Kidney neoplasm, small cell carcinoma, combined therapeutic regimen,Urinary system