摘要
Polymeric micelles were prepared by dropping ethanol into solutions containing（poly（γ-benzyl L-）glutamate）-poly（ethylene oxide） block copolymer （PBLG-b-PEO）,chloroform（CHCl3） and trifluoroacetic acid（TFA）.Viscometry,transmission electron microscopy（TEM）,nuclear magnetic resonance（（）1H-NMR） spectroscopy and infra-red difference spectroscopy（IR） were used to investigate the influence of PBLG chain conformation on the self-assembly behavior of PBLG-b-PEO.The experimental results revealed that PBLG-b-PEO could associate into polymeric micelles in ethanol solutions.The introduction of TFA not only changes the conformation of PBLG segments,but also increases the critical micelle concentration,and further affects the morphologies of the formed micelles.
Polymeric micelles were prepared by dropping ethanol into solutions containing poly（ γ-benzyl L- glutamate）-poly （ ethylene oxide ） block copolymer （ PBLG- b-PEO ）, chloroform （ CHCl3 ） and trifluoroacetic acid （TFA）. Viscometry, transmission electron microscopy （TEM）, nuclear magnetic resonance （ ^1 H-NMR） spectroscopy and infra-red difference spectroscopy （IR） were used to investigate the influence of PBLG chain conformation on the self-assembly behavior of PBLG-b-PEO. The experimental results revealed that PBLG-b-PEO could associate into polymeric micelles in ethanol solutions. The introduction of TFA not only changes the conformation of PBLG segments,but also increases the critical micelle concentration, and further affects the morphologies of the formed micelles.
出处
《高分子学报》
SCIE
CAS
CSCD
北大核心
2006年第5期732-735,共4页
Acta Polymerica Sinica
基金
国家自然科学基金(基金号50273011
20574018)
上海市曙光计划(项目号02SG025)
教育部博士点基金(基金号20050251008)
上海市科学技术委员会纳米专项基金(基金号0352nm109)资助项目
关键词
聚肽共聚物
自组装
临界胶束浓度
分子链构象
Polypeptide copolymer, Self-assembly, Critical micelle concentration, Chain conformation
作者简介
通讯联系人,E-mai1：jplinlab@online.sh.cn
