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IL-10与器官移植 被引量:2

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摘要 白细胞介素10(interleukin 10,IL-10)于1989年由Fiorentino等[1]发现,他们证明IL-10由Th2淋巴细胞和单核细胞合成分泌,具有抗炎和抑制多种细胞因子合成的作用,所以称之为细胞因子合成抑制因子(cytokine synthesisinhibitingfactor,CSIF).人的IL-10(hIL-10)基因定位于第一号染色体上.在氨基酸水平,hIL-10与病毒IL-10(vIL-10)有84%的同源性,与鼠IL-10有73%的同源性.
作者 张栋 高东宸
出处 《中华肝胆外科杂志》 CAS CSCD 2006年第7期500-502,共3页 Chinese Journal of Hepatobiliary Surgery
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同被引文献31

  • 1高思海,李平,潘铁成,龚非力,杨辰垣.白细胞介素10基因转染抑制小鼠心脏移植排斥反应的实验研究[J].中华器官移植杂志,2004,25(6):349-350. 被引量:8
  • 2陈斌,彭荣章.IL-10与急性排斥反应[J].河南科技大学学报(医学版),2005,23(1):76-78. 被引量:1
  • 3唐春华,凌建煜.IL-10及其在器官移植中的应用[J].上海交通大学学报(医学版),2006,26(6):699-700. 被引量:3
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