摘要
目的:研究屏风固金颗粒抑菌抗炎作用。方法:采用体内体外相结合的方法观察屏风固金颗粒抑菌作用;通过小鼠腹腔毛细血管通透性实验、二甲苯致小鼠耳廓肿胀实验及大鼠蛋清性足趾肿胀实验测定其抗炎作用。结果:屏风固金颗粒在体外对常见的多种致病菌有不同程度的抑制作用,在体内对感染金黄色葡萄球菌和表皮葡萄球菌的小鼠有明显的保护作用;能明显抑制小鼠腹腔毛细血管通透性亢进、二甲苯致小鼠耳廓肿胀及蛋清性大鼠足肿胀。结论:屏风固金颗粒具有抑菌抗炎作用。
ORJECTIVE To study the bacteriostasis and anti-inflammatory effects of Pingfeng Gujin granules（PFGJG）. METHODS The bacteriostasis of PFGJG was investigated in vivo and in vitro. Anti-inflammatory effects of PFGJG was observed by the celiac capillary permeability, ear edema induced by xylene in mice, and the foot edema induced by egg white in rats. RESULTS PFGJG had suppressive function in different degree on many common pathogenic in vitro and it also had significant protective effect against staphylococcus aureus and staphylococcus epidermidi in mice. PFGJG evidently inhibited the excessive celiac capillary permeability, ear edema induced by xylene in mice, and the foot edema induced by egg white in rats. CONCLUSION PFGJG has obvious bacteriostasis and anti-inflammatory effects.
出处
《中国医院药学杂志》
CAS
CSCD
北大核心
2006年第7期834-836,共3页
Chinese Journal of Hospital Pharmacy
关键词
屏风固金颗粒
抑菌作用
抗炎作用
Pingfeng GuJin granule
bacteriostasis
anti-inflammatory effects
作者简介
魏爱英，女，学士，副主任药师，电话：0531—86881196，E-mail：sdslyy_way@163．com
