摘要
目的探讨立体定向放射治疗后复发性肝癌和放射性肝损伤的MR I诊断价值。方法26例原发性肝癌立体定向放射治疗后怀疑复发的患者行MR I T1W I、T2W I和T1W I动态增强检查,测量复发性肝癌和放射性肝损伤的T1W I、T2W I的信噪比及强化程度,并进行统计学分析。结果复发性肝癌和放射性肝损伤在T1W I和T2W I上信号表现相似,两者信噪比(SNR)对比差异无显著性。动态扫描后,复发性肝癌在动脉期强化,静脉期及延迟期呈低信号,强化持续时间短;放射性肝损伤动脉期强化,强化持续时间长,静脉期及延迟期亦呈高信号,两者明显不同。结论MR I动态增强可有效地鉴别复发性肝癌和放射性肝损伤。
Objective To assess the value of MRI imaging in the differentiation between a recurrent hepatocellular carcinoma and radiation-induced hepatic injury. Methods Twenty-six patients with suspected recurrent hepatocellular carcinoma after radiotherapy underwent MRI T1 WI, T2 WI and Gd-DTPA enhanced dynamic studies. Signal-to-noise ratios in T1 WI ,T2WI and the percentage enhancement at the hepatic injury area and recurrent hepatocellular carcinoma were calculated. Results Recurrent hepatocellular carcinoma and the radiation-induced hepatic injury area showed similar image characteristics：hypointense signal in T1 WI and hyperintense signal in T2WI. Signal-to-noise ratios in T1 WI and T2WI were not significantly different. In the gadolinium-enhanced dynamic study, the recurrent hepatocellular carcinoma showed early enhancement, followed by a rapid washout. However, the irradiated liver parenchyma showed hyperintensity in early phase, and the contrast enhancement tended to be more prominent and prolonged till the end of the dynamic study. Conclusion The characteristic findings of the dynamic MRI study enable us to distinguish between recurrent hepatocellular carcinoma and radiation-induced hepatic injury.
出处
《中国肿瘤临床与康复》
2006年第3期241-243,共3页
Chinese Journal of Clinical Oncology and Rehabilitation
作者简介
吕国士，男，内蒙古集宁市人，博士研究生，主治医师，从事CT、MRI诊断专业。
