摘要
目的:采用气相色谱法测定精制狗皮膏中樟脑、薄荷脑、龙脑、水杨酸甲酯的含量。方法:气相色谱法,弹性石英毛细管柱(30m×0.32mm×0.25μm),聚乙二醇(PEG)-20M为固定液,FID检测器。结果:所测樟脑、薄荷脑、龙脑、水杨酸甲酯之间具有良好的分离效果,樟脑的经性范围为160～960μg/ml,平均回收率101.1%,RSD为2.74%;薄荷脑的线性范围为160～960μg/ml,平均回收率102.2%,RSD为2.42%;龙脑的线性范围为40～240μg/ml,平均回收率101.4%,RSD为2.15%;水杨酸甲酯的线性范围时80～480μg/ml,平均回收率102.0%,RSD为2.54%。结论:本方法简便、快速、结果准确,可用于精制狗皮膏的质量控制。
Objective：The purpose is to develop GC method for the assay of Camphor,Menthol,Borned and methyl salicylate in Jingzhi Goupi Gao. Method：GC was applied to quantitative analysis. Chromatographic conditions was resilience capillary of quartz with PEG-20M ;Flame ionization detector （FID）. Results：Camphor,Menthol ,Bormeol and Methyl Saliylate were separated completely. The linear range of Camphor was 160～960μg/ml. The average recovery was 101.1% with RSD= 2.74 % （n ： 5） ;The linear range of Menthol was 160% 960μg/ml. The average recovery was 102.2 % with RSD=2. 42 % （n = 5）%The linear range of Borneol was 40～ 240μg/ml. The average recovery was 101.4 % with RSD= 2.15 % （n=5） ;The linear range of Methyl Salilylate was 80～ 480μg/ml. The average recovery was 102.0% with RSD= 2.54 % （n=5）. Conclusion ：The established method is accurate and it can be applied to quality control of Jingzhi Goupi Gao.
出处
《中国药品标准》
CAS
2006年第3期34-36,共3页
Drug Standards of China
