摘要
Noni juice （Morinda citrifolia） has been approved for use as a safe food within the European Union, following a review of safety. Since approval, three cases of acute hepatitis in Austrian noni juice consumers have been published, where a causal link is suggested between the liver dysfunction and ingestion of anthraquinones from the plant. Measurements of liver function in a human clinical safety study of TAHITIAN NONI Juice, as well as subacute and subchronic animal toxicity tests revealed no evidence of adverse liver effects at doses many times higher than those reported in the case studies. Additionally, M. citrifolia anthraquinones occur in the fruit in quantities too small to be of any toxicological significance. Further, these do not have chemical structures capable of being reduced to reactive anthrone radicals, which were implicated in previous cases of herbal hepototoxicity. The available data reveals no evidence of liver toxicity.
Noni 果汁(Morinda citrifolia ) 在欧盟以内用作安全食物被同意了，跟随安全的评论。自从赞同，在奥地利人的尖锐肝炎的三个案例非， i 果汁消费者被出版了，在一个原因的连接从植物在肝机能障碍和 anthraquinones 的摄取之间被建议的地方。人的临床的安全地的肝功能的大小 TAHITIAN NONI 果汁学习，以及稍尖并且代替揭示的长期的动物毒性试验不利的肝的证据都不比那些在案例研究报导在多次高的剂量完成。另外， M。citrifolia anthraquinones 在太小而无法具有任何毒物学的意义的数量发生在水果。进一步，这些没有能够被归结为的化学结构反应一个王位激进分子，它在草药的 hepototoxicity 的以前的情况中被含有。可得到的数据不揭示肝毒性的证据。
作者简介
Brett J West, Research and Development, Tahitian Noni International, American Fork, UT 84003, United States. brett_west@tni.com Telephone： ＋1-801-2343621 Fax： ＋1-801-2341030
