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焦炉工GSTM1基因多态性与血清丙二醛关系的研究

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摘要 目的探究焦炉作业工人代谢酶基因多态性与血清MDA关系。方法选取109名焦炉作业工人作为研究对象,用PCR扩增技术将其按GSTM1基因型分为2组,分别测定其血清MDA值,使用SAS软件进行比较。结果比较GSTM1缺失基因型个体血清MDA水平与GSTM1正常基因型个体血清MDA水平,两组差异无统计学意义(P>0·05)。结论未发现GSTM1基因多态性影响血清MDA水平。
作者 张索磊 王新朝 吴逸明
机构地区 郑州大学公共卫生学院劳动卫生学及卫生毒理学教研室
出处 《卫生研究》 CAS CSCD 北大核心 2006年第3期353-354,共2页 Journal of Hygiene Research
基金 国家自然科学基金资助项目(No.30571552) 教育部"211工程"重点学科研究项目"肿瘤与生物工程"子项目
关键词 焦炉工 GSTM1 基因多态性 MDA 肺癌
分类号 R135.2 [医药卫生—劳动卫生] R734.2 [医药卫生—肿瘤]
作者简介 张索磊,男,硕士研究生 通讯作者
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参考文献11

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二级参考文献31

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卫生研究
2006年 第3期

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