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过敏性哮喘特异性免疫治疗的机制 被引量:12

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摘要 特异性免疫治疗被认为是过敏性哮喘的完整治疗方案的组成部分和针对哮喘病因的唯一治疗方法。其机制至今仍不完全清楚,但已有很大进展。最近的研究主要涉及逆转Th1/Th2平衡失调,调节性T细胞(CD4+CD25+Tr)对免疫应答的抑制性调节,诱导外周耐受,重组保留T细胞表位而改变B细胞表位的变应原,给予免疫刺激序列等。本文综述了近几年来对特异性免疫治疗机制的研究。
作者 王模奎 黄英
出处 《国际呼吸杂志》 2006年第5期366-368,共3页 International Journal of Respiration
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