期刊文献+

肺隐球菌病的外科治疗 被引量:34

Surgical treatment of pulmonary cryptococcosis
原文传递
导出
摘要 目的探讨肺隐球菌病的临床特点、诊断、手术治疗及疗效。方法分析27例外科手术治疗的肺隐球菌病患者,其中男22例,女5例;年龄25~67岁,平均(47.5±7.9)岁。其中标准剖胸手术17例,采用胸腔镜或胸腔镜辅助下小切口开胸手术10例;肺叶切除16例,肺局部楔形切除9例,胸腔镜活检术2例。结果病灶彻底切除25例,2例胸腔镜活检。无手术死亡病例,术后无胸腔内出血,切口愈合良好,无切口感染,无脓胸以及支气管胸膜瘘等。随访2~5年,25例治愈、无复发,1例复发且伴有隐球菌脑膜炎,1例失访。结论肺隐球菌病的临床表现和影像学检查缺乏特征性表现,外科手术是诊断及治疗局限性肺隐球菌病非常有效的手段,胸腔镜或胸腔镜辅助小切口手术具有创伤小、恢复快的特点。 Objective To summarize the clinical features, diagnosis and surgical experience of pulmonary cryptococcosis. Methods Twenty-seven patients with pulmonary cryptococcosis were treated surgically. There were 22 males and 5 females. The mean age at operation was (47. 5 ±7.9)years. Open thoracotomy was performed for 17 patients, thoracoscopic surgery or video-assisted minithoractomy surgery was performed for 10 patients ;lobectomy was performed for 16 patients, pulmonary wedge resection was done for 9 patients;thoracoscopic pulmonary biopsy was conducted in 2 patients. Results Complete removal of lesion was obtained in 25 patients and pulmonary biopsy was obtained in 2 patients. The 26 patients were fallowed up for 2 to 5 years, and 25 of them were cured. There was no post-operative deaths and no complications in the 25 patients. The complication of meningitis and recurrence were found in only one case. Conclusions Pulmonary eryptococeosis shows no specific clinical features and X-ray manifestations. For localized pulmonary ctyptococcosis, surgical resection may be an effective procedure for its diagnosis and treatment. Because of its minimal invasiveness and short length of hospital stay, thoracoscopic surgery may be suverior to oven thoraeotomy.
作者 刘明 姜格宁
出处 《中华结核和呼吸杂志》 CAS CSCD 北大核心 2006年第5期307-309,共3页 Chinese Journal of Tuberculosis and Respiratory Diseases
关键词 肺隐球菌病 诊断 外科治疗 vPulmonary cryptococcosis Diagnosis Surgical treatment
  • 相关文献

参考文献11

  • 1Hammerman KJ, Powell KE, Christianson CS, et al. Pulmonary cryptococcosis:clinical forms and treatment. A Center for Disease Control cooperative mycoses study. Am Rev Respir Dis, 1973,108 :1116-1123.
  • 2易祥华,张容轩,高文,张敏,马前立,汪浩.临床酷似肺癌的肺隐球菌病12例临床病理分析[J].诊断病理学杂志,2001,8(6):330-333. 被引量:26
  • 3Nunez M,Peacock JE Jr,Chin R Jr. Pulmonary cryptococcosis in the immunocompetent host. Therapy with oral fluconazole: a report of four cases and a review of the literature. Chest,2000,118:527-534.
  • 4Baughman RP, Rhodes JC, Dohn MN, et al. Detection of cryptococcal antigen in bronchoalveolar lavage fluid: a prospective study of diagnostic utility. Am Rev Respir Dis, 1992,145 : 1226-1229.
  • 5Dromer F, Mathoulin S, Dupont B, et al. Comparison of the efficacy of amphoteficin B and fluconazole in the treatment of cryptoeoecosis in human immunodeficiency virus-negative patients: retrospective analysis of 83 cases. French Cryptoeoccosis Study Group. Clin Infect Dis, 1996,22 Suppl 2 : S154-S160.
  • 6Yamaguchi H, Ikemoto H, Watanabe K, et al. Fluconazole monotherapy for cryptococcosis in non-AIDS patients. Eur J Clin Microbiol Infect Dis, 1996,15:787-792.
  • 7Yew WW, Wong PC, Wong CF, et al. Oral fluconazole in the treatment of pulmonary cryptococcosis in non-AIDS patients. Drugs Exp Clin Res, 1996,22:25-28.
  • 8Saag MS,Gmybill RJ,Larsen RA,et al. Practice guidelines for the management of cryptococcal disease. Infectious Diseases Society of America. Clin Infect Dis,2000,30:710-718.
  • 9Fukuhara T,Makihara S,Umemori Y,et al. Three resected cases of pulmonary cryptococcosis. Kyobu Geka, 1998,51:801-805.
  • 10赖国祥,张玉华,林庆安,柳德灵.国内22年肺隐球菌病回顾性分析[J].中国实用内科杂志,2005,25(2):176-178. 被引量:96

二级参考文献7

共引文献116

同被引文献271

引证文献34

二级引证文献193

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部