摘要
目的探讨血清瘦素水平对老年男性骨质疏松的影响。方法选取年龄在60～92岁的158例老年男性,采用双能X线法(DXA)检测骨密度,并根据测值将受试者分为骨质疏松组与非骨质疏松组,用放射免疫法(RIA)检测两组空腹血清瘦素浓度,进行比较研究。结果血清瘦素测值在不同年龄组间的差异无统计学意义,而在肥胖组与非肥胖组间有显著差异(P<0.01)。在老年男性骨质疏松组血清瘦素测值明显低于非骨质疏松组,两者具有显著差异(P<0.05)。结论血清瘦素测值并不随老年男性的年龄而变化,但与老年男性的体重指数呈正相关,血清瘦素对老年男性骨质疏松有较好的预示及保护作用。
Objective To investigate the relationships between serum leptin concentration and osteoporosis in elder men. Methods Totally, 158 elder men, aged 60 - 92, were choosen and bone mineral density （BMD）were measured by dual energy X-ray ahsorptiometry（DXA）. They were divided into osteoporosis and healthy groups according to BMD results. Fasting serum concentrations of leptin were measured by radioimmunoassay （ RIA）. Results No statistical difference was found among different age groups, but the serum leptin concentration was positively correlated with body mass index（BMI） and BMD,respectively. Conclusions Serum leptin concentration plays an important role in maintaining bone mass and bone quality and is a good index for osteoporosis in elder men.
出处
《中国骨质疏松杂志》
CAS
CSCD
2006年第2期164-165,共2页
Chinese Journal of Osteoporosis
作者简介
通讯作者：庞小芬，Email：xiaofenpang@126．com
