摘要
采用HPLC反相法及RLA法测围产期母子血清25(OH)Da、PTH、CT、C_a、P、AKP水平。结果示健康孕妇VitD代谢处于正常生理调节范围,给孕妇补充VitD仅可提高母子25(OH)D_3水平及胎儿PTH水平。提示健康妇女可适应妊娠这一特殊的生理现象,但孕后期适量补充VitD对新生儿有益。
The serum values of the 25 (OH) D3 PTH、CT、Ca、P and AKP in pregnant women,cords and neonates were measured by the methods of HPLC and RIA. The results showed that there were no significant changes of regulation for mother's VitD metabolism during the gesta-tional period. In late pregnancy the VitD supplementation could only increase the levels of 25 (OH)D3 both in mothers and fetuses as well as the levels of PTH in cord blood. These data indicate that the women can gradually adapt to the physiologic changes by a regulating mechanism during normal gestational period. However,supplementation of the VitD may be helpful to the neonates.
