摘要
目的:评价下牙槽神经、舌神经干注射阿霉素联合颊神经撕脱治疗三叉神经(Ⅲ支)痛的疗效。方法:对41例三叉神经痛患者进行单纯下牙槽、舌神经干注射阿霉素的治疗,52例进行神经干注射阿霉素联合颊神经撕脱治疗。对2组术后3a、5a的复发率进行χ2检验。结果:单纯注射阿霉素组,37例疼痛症状消失,4例症状缓解;联合颊神经撕脱组,52例疼痛症状全部消失。随访3a,前者的复发率为12.2%,后者为3.8%(P>0.05);随访5a,前者的复发率为21.9%,后者为5.8%(P<0.05);随时间延长,2组间的复发率差异加大。结论:神经干注射阿霉素联合颊神经撕脱术,可提高神经干注射阿霉素治疗三叉神经(Ⅲ支)痛的疗效,减少其复发率。
PURPOSE： To evaluate the clinical therapeutic efficacy by injecting adriamycin to the inferior alveolar and lingual nerve and avulsion of the buccal nerve in primary trigeminal neuralgia （the third branch）. METHODS： Adriamycin was injected to the lingual nerve and inferior alveolar nerve in primary trigeminal neuralgia of 41 cases; adriamycin injection combined with avulsion of the buccal nerve was applied in another 52 cases of primary trigeminal neuralgia. The recurrence rate for 3 years and 5 years was analyzed by Chi-square test. RESULTS： ;In the group of injection of adriamycin, the symptom of pain disappeared in 37 patients and decreased in 4 patients after treatment. The recurrence rate was 12.2% in 3 years and 21.9% in 5 years. In the group of combined treatment, the symptom of pain disappeared in all cases. The recurrence rate was 3.9%（P〉0.05） in 3 years and 5.8% （P〈0.05） in 5 years. The difference of recurrence rate between the two groups increased with the lapse of time. CONCLUSION： Combined injection of adriamycin to the nerve trunk and avulsion of the buccal nerve in primary trigeminal neuralgia can improve the therapeutic efficacy,and decreased recurrence.
出处
《中国口腔颌面外科杂志》
CAS
2006年第2期117-119,共3页
China Journal of Oral and Maxillofacial Surgery
关键词
原发性三叉神经痛
阿霉素
神经撕脱术
Primary trigeminal neuralgia
Adriamycin
Avulsion of nerve
作者简介
唐西清（1965-），男，学士，副主任医师
【通讯作者】曹放云，Tel：0734—8288932（O），13187237366（M），E-mail：txq5565@163．com.
