摘要
金属硫蛋白(MT)是一类主要合成于肝脏的低分子量金属结合蛋白,主要参与体内必需金属元素的储存、代谢、转运和解毒等过程,近年发现MT同时是一种很强的内源性细胞保护物质,尤其在精神应激等损伤中发挥重要保护作用。结合中医“肝主疏泄”理论,探讨MT与肝脏的密切联系及其与中医调肝治法和抗应激损伤的关系,对于阐明肝主疏泄的实质有一定启示。
Metallothioneins （MT） is a group of lower moleeular weight metal- binding proteins characterized by containing abundant of cysteine and were synthesied in the liver of mammal., which are thought to be participated in storage , metabolize and transfer of essential metal elements , also detoxifcate of heavy metals, elimination of free radicals, stress reaction, embryonic development , regulation of cellular metabolization, internal secretion and formation of tumor. MT is a cell protective factor , and its synthesize could be inducted in tissue regeneration development process , exogenous and endogenous factors . In theory of Traditional Chinese Medicine , liver has the function of ＂liver bears the depressive effect＂, which is believed to be the major organ of restraint stress , the relation between MT and ＂liver bears the depressive effect＂ was investigated in this article by referencing the connecting of the two facors which had the significance for explaining the scientific of connotative meaning of .＂ liver bears the depressive effect＂.
出处
《辽宁中医杂志》
CAS
北大核心
2006年第2期154-156,共3页
Liaoning Journal of Traditional Chinese Medicine
基金
中国博士后科学基金(2004036492)
关键词
金属硫蛋白
肝
应激
综述
metallothioneins
liver bears the depressive effecte
restraints tress
preview
作者简介
张晓文（1965-），男，甘肃白银人，副研究员，在站博士后，主要从事中医藏象理论研究。
