摘要
目的：探讨宫颈上皮内瘤样病变（CIN）Ⅱ-Ⅲ患者高频电波刀宫颈电圈环切术（LEEP）治疗的有效性。方法：对CINⅡ-Ⅲ行LEEP手术的73例患者进行为期2—5年的随访，对手术后患者的病灶持续存在和复发等情况进行分析总结。结果：6个月总的治愈率为97．26％，病变持续存在率2．74％，术后1年复发率为2．78％，2年时复发率为1．41％，3年、4年、5年无复发。其中CINⅡ33例，6月治愈率96．97％，病变持续存在率3．03％，1年复发率为0.2年复发率为3．23％；CINⅢ40例，6月治愈率为97．50％，病变持续存在率2．50％，1年复发率5．00％；CINⅡ、CINⅢ在治愈率、病变持续存在率、复发率方面比较差异无显著性（P〉0．05）。结论：LEEP对于CINⅡ-Ⅲ患者的治疗是安全、有效的，但需长期随访，尤其是术后前2年。
Objective： To determine the effectiveness of loop electrosurgicai excision procedure （LEEP） for the management of cervical intraepithelial neoplasia （CIN） Ⅱ-Ⅲ. Methods： 73 patients of CINⅡ-Ⅲ treated by LEEP were followed up for 2 - 5 years in our department. The incidences of residual and the recurrence were reviewed prospectively. Results：The overall cure rate in this study was 97.26% after first 6 month LEEP. The residual CIN was identified in 2.74% patients. The recurrent CIN occurred in 2.78% patients in the first year, 1.41% in the 2nd year, none in the 3rd ,4th and 5th year. According to the grade of disease, in 33 cases of CIN Ⅱ, the overall cure rate was 96.97% after first 6 month LEEP, residual CIN was identified in 3.03% patients, the recurrent CIN occurred in none patients in the first year,3.23% in the 2nd year, none in the 3rd ,4th and 5th year. In 40 cases of CINⅢ, the overall cure rate was 97.50% after first 6 month LEEP, the residual CIN occurred in 2.50% patients, and recurrent CIN took place in 2.50% patients in the first year, none in the 2nd,3rd ,4th and 5th year, no difference was shown between CINⅡ and CINⅢ （ P〉 0.05）.Conclusions： LEEP is a kind of effective and safe method for the treatment of CIN Ⅱ-Ⅲ. But the patients need to be followed for a long time, especially in the first two years.
出处
《实用妇产科杂志》
CAS
CSCD
北大核心
2006年第1期37-39,共3页
Journal of Practical Obstetrics and Gynecology
关键词
宫颈上皮内瘤样病变
高频电波刀宫颈电圈环切术
治愈率
复发率
Cervical intraepithelial neoplasia （CIN）
Loop electrosurgical excision procedure （LEEP）
The cure rate
The recurrence rate
