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龙岗区出生缺陷筛查干预模式的探讨 被引量:4

Approach to Screeing and Intervention Pattern of Birth Defects in Longgang Area
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摘要 目的:掌握深圳市龙岗区重点出生缺陷疾病的发生水平,探讨出生缺陷筛查干预的新模式。方法:利用日趋完善、初具技术水平及规模和具备优生咨询及群体筛查等技术实力的计划生育服务网络,对龙岗区10个镇(街道办)的人口出生缺陷进行筛查干预,建立一个大面积人群筛查-高风险夫妇产前诊断-医学建议-选择性流(引)产的体系,并发挥其正常功能。结果:干预后育龄人群对有关出生缺陷知识及基线答对率(83±3.6)%比干预前(42±6.5)%有显著提高(P<0.01)。结论:探讨目前既经济又有效的人口出生缺陷筛查干预模式,对降低龙岗区出生缺陷(尤其是重症缺陷)患儿的发生率,提高出生人口素质显得十分必要。 Objective: To master the incidence of important birth defects in Longgang area of Shenzhen, To discuss new pattern screening and intervention of birth defects. Methods : We utilize the family planning service network of gradual perfection and initial technology scale which have a good birth consultation and group screening technology, giving screening and intervention of birth defects for ten streets in Longgang area to build a system of large - Scale people test - prenatal diagnosis of high risk married couple - medicine proposal - selective artifical abortion. Results: There is remarkable promotion on knowledge and basic right reply rate of birth defects (P 〈0. Ol ) after intervention (83 +3. 6)% than before intervention (42 +6. 5)%. Conclusion: It is very necessary to find an economical and effective mode of screening and intervention of birth defects, which can reduce the rate of birth defects ( especially main defects) and raise the quali- ty of birth population.
出处 《中国妇幼保健》 CAS 北大核心 2006年第3期301-302,共2页 Maternal and Child Health Care of China
关键词 出生缺陷 筛查 干预 模式 Birth defects Screening Intervention Pattern
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  • 1徐湘民,廖灿,刘忠英,黄以宁,张基增,李坚,彭朝辉,邱洛琳,蔡旭恒.β地中海贫血的大人群筛查及产前诊断[J].中华医学遗传学杂志,1996,13(5):258-261. 被引量:69
  • 2杜传书.地中海贫血研究的现状与未来[J].中华医学遗传学杂志,1996,13(5):257-257.
  • 3Hsu J J, Hsieh TT, Hsieh FJ. Down' s syndrome screening in an Asian population using alpha-fetoprotein and free β-HCG: a report of the Taiwan Down' s syndrome screening group. Obstet Gynecol,1996,87 (6): 943-947
  • 4Cuckle HS,Wald NJ ,Thompson SG. Estimating a woman's risk of having a pregnancy associated with Down' s syndrome using her age and serum alpha-fetoprotein level. Br J Obstet Gynaecol, 1987,94(5): 387-402
  • 5Chik L, Spencer K, Johnson MP, et al. Precise gaussian distribution functions of maternal serum α-fetoprotein and free β-subunit of human chorionic gonadotropin for trisomy 21 screening:improved accuracy for patient counseling. Am J Obstet Gynecol, 1997
  • 6O'Brien WF,Knuppel RA, Torres C, et al. Potential prenatal predictions of Down' s syndrome: a statistical analysis. Am J Obstet Gynecol, 1990,163(6 Pt 1) : 1796-1798
  • 7Hsu JJ,Hsieh TT, Soong YK, et al. Comparison of Down's syndrome screening strategies in Asians combining serum free betahCG and alpha-fetoprotein with maternal age. Prenat Diagn, 1997,17(8) :707-716
  • 8Spencer K. Screening for Down' s syndrome: the role of intact hCG and free subunit measurement. Scand J Clin Lab Invest, 1993,53(suppl 216): 79-96
  • 9Hsu J J, Chiu TH, Chen KC, et al. Maternal serum alpha-fetoprotein levels between 13 and 24 weeks' gestation. Chang Gung Med J,1994,17 (12): 309-315
  • 10徐湘民.见于中国人的HPFH和δ β-地中海贫血的分子基础[J].中华医学遗传学杂志,1998,15(5):315-317. 被引量:31

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