摘要
微囊藻毒素是由淡水蓝藻产生的一类具有肝毒性的生物活性物质。它能够抑制蛋白磷酸酶1和蛋白磷酸酶2A的活性,使细胞内的蛋白磷酸化和去磷酸化失衡。微囊藻毒素能够对人体产生一系列的危害,如肝毒性、肾毒性、肠毒性和促癌作用等。
Mierocystins are a group of toxins that are produced hy fresh water cyanobacteria. They are bioaetive materials which are bepatotoxic. They can inhibit serine/threonine protein phosphatase （PP1 and PP2A）, breaking the balance between protein phosporylation and phosphorylysis. They present a wide range of harmful effects to human bedy, such as hepatotoxicity and tumor promotion. They also affect other organs like kidney and intestines. Recently, more and more attention is being paid to microcysfins worldwide. This review summarizes the progress in the toxicological study of fresh water microcystins.
出处
《卫生研究》
CAS
CSCD
北大核心
2006年第1期120-122,共3页
Journal of Hygiene Research
基金
人事部留学回国基金
关键词
淡水藻华
微囊藻毒素
毒理学
fresh water algal bloom, micorcystins, toxicology
作者简介
陈国永，男，硕士研究生
通讯作者
