摘要
目的:观察三维适形放疗联合多烯紫杉醇治疗局部晚期非小细胞肺癌的近期疗效。方法:83例局部晚期非小细胞肺癌患者(Ⅲa期或Ⅲb期)随机分为治疗组与对照组。对照组仅行三维适形放疗,治疗组给予三维适形放疗联合多烯紫杉醇治疗。结果:治疗组与对照组有效率分别为88.37%、62.50%(P<0.05);治疗组白细胞下降的发生率高于对照组(P<0.05),但予以粒细胞集落刺激因子或巨噬细胞粒细胞集落刺激因子后,均可完成治疗。结论:三维适形放疗联合多烯紫杉醇治疗局部晚期非小细胞肺癌近期疗效好。
OBJECTIVE： To observe the short-term curative effects of 3- dimensional conformal radiotherapy（3DCRT） combined with taxotere on locally advanced non small cell lung cancer.METHODS： 83 patients Ⅲa or Ⅲb with locally advanced non-small cell lung cancer were divided randomly into the treatment and control group .The treatment group were treated with 3DCRT in combination with taxotere, while the control group were treated with single 3DCRT.RESULTS： The effective rates in the treatment and control group were 88.37% and 62.50% （P〈 0.05）, respectively .The incidence of leukocyte decrease was higher in the treatment group than that in the control group（P 〈0.05）, but the treatment was completed after the administration of granuloeyte colony stimulating factor or macrophage colony - stimulating factor.CONCLUSION ：Shortterm curative effects of 3DCRT combined with taxotere on locally advanced non-small cell lung cancer are found to be good.
出处
《中国药房》
CAS
CSCD
北大核心
2006年第2期126-128,共3页
China Pharmacy
关键词
局部晚期非小细胞肺癌
三维适形放疗
多烯紫杉醇
Locally advanced non small cell lung cancer
3 dimensional conformal radiotherapy
Taxotere
作者简介
李雪松：主治医师。研究方向：肿瘤放疗。电话：0816-2230478。E-mail：daitangzhi@tom．com
