摘要
雷奈酸锶是一种新近上市的治疗骨质疏松药物,能够有效预防和治疗骨质疏松症及绝经后妇女骨质疏松引起的骨折。大量的动物实验和临床试验研究表明雷奈酸锶是一种既具有抗骨吸收,又能促进骨形成的药物。在迄今为止的临床试验中,雷奈酸锶显示了很好的安全性和有效性。本文就雷奈酸锶目前的药理及临床研究进展作一综述。
Strontium ranelate is a new available medicine in the treatment of osteoporosis possessing effective prevention and treatment for osteoporosis especially in the management of bone fracture induced by postmenopausal asteoporosis.A lot of animal experiments and clinical trials have proven that strontium ranelate not only can prevent bone absorption but also promote bone formation. Up to date, strontium ranelate displays safety and effectiveness in the clinical study.The mechanism of pharmacology and recent advance in clinical trials of strontium ranelate are reviewed in this paper.
出处
《中国新药与临床杂志》
CAS
CSCD
北大核心
2006年第1期70-74,共5页
Chinese Journal of New Drugs and Clinical Remedies
关键词
骨质疏松
药物疗法
临床试验
雷奈酸锶
osteoporosis
drug therapy
clinical trials
strontium ranelate
作者简介
蒋晔（1961-），男，河北石家庄人，教授，硕土生导师，主要从事药学教育和新药开发工作。[联系人]蒋晔。Phn：86—311-8626—6069，86—311—8626—5623。E-mail：jiangye@hehmu．edu．cn，jiangyel@sina．ocm．cn
