摘要
传统化学制药的黄金时代结束,新化学药品数量下降,而生物技术药物已成为当今最活跃和发展最迅速的领域。随着基因组和蛋白质组研究的深入,越来越多与人类疾病发展相关的靶标被确定,生物制药将有更多的机会获得突破性进展。综述了全球生物制药产业发展的几个态势,主要有(1)全球生物制药产业的研究成果数量增长迅速;(2)生物制药依然是生物技术产业的重点领域,生物技术药物市场发展规模逐渐扩大,市场集中度高,主要集中于美国和大的跨国公司;(3)生物技术新药在新药研发中的比重越来越大,逐渐成为新药研发主流;(4)生物制药企业间通过加强联盟,来增强新药研发能力和降低新药研发成本;(5)各国政府均重视生物制药产业的发展,出台一系列相关政策。(6)生物疫苗、基因工程药物和基因药物具有良好的市场前景。
The number of new medical products based on chemistry launches at the lowest level for many years. The pharmaceutical industry puts emphasis on biotechnology-derived products. Both genomics and protemics are contributing to understanding and determining more targets which involved in human disease. This means that there will be more opportunities for biopharmaceutical breakthroughs, eventually, more and better biomedicines will be approved. Several trends in development for biopharmaceuticals were analyzed： （1） Biological medicine and Chinese traditional medicine have developed rapidly between 1998 - 2005, the number of the papers about biological medicine increases dramaticly. （2） The emphasis is on biological medicine in pharmaceutical industry and the biotech market is concentrating in United States and multinational. （ 3 ） The proportion of biotech products is becoming larger gradually. More concern is focused on biotech products. （4） In order to reduce the cost of R＆D and increase the number of new drugs, more and more M＆A occur between the biotech companies. （5） The governments all over the world attach importance to biotech products. （ 6 ） Tissue engineering, cell therapy and gene therapy have a good future, full of opportunities and challenges.
出处
《中国生物工程杂志》
CAS
CSCD
北大核心
2006年第1期92-96,共5页
China Biotechnology
关键词
生物制药
NCEs
生物技术药物
市场
Biopharmaceutical NCEs Biotechnology-derived medicine Market
作者简介
电子信箱：smwen@sibs．ac．cn
