摘要
目的探讨狼疮性肾炎(LN)并发医院感染(nosocomialinfection,NI)的易感因素和细菌学特点。方法评价LN并发NI的细菌学特征和实验室指标与NI的关系。结果63例LN中,23例(31例次)发生NI,感染率为36.51%,感染例次率为49.21%。最常见的病原菌是大肠埃希菌,其次是肺炎克雷白菌和白色念珠菌。贫血、营养不良、低IgG血症、大量蛋白尿、肾功能不全、狼疮活动、大剂量使用抗生素和激素等是导致LN易发生NI的因素。结论LN易并发NI,最常见的病原菌是大肠埃希菌,其次是肺炎克雷白菌和白色念珠菌;易感因素有贫血、营养不良、低IgG血症、大量蛋白尿、肾功能不全、狼疮活动、大剂量使用抗生素和激素等,值得临床医生重视。
Objective To investigate the bacteriologic characteristics and influencing factors of nosocomial infection (NI) in patients with lupus nephritis (LN). Methods The bacteriologic characteristics and laboratorial indexes were analyzed in patients with and without NI secondary to LN. Result The incidence of NI in patients with LN was 36.51%. The most common germ was escherichia coli, the second was ldebsiella pneumonia and fungus. The factors related to NI were anemia, malnutrition, hypogammaglobulinemia, mass proteinufia, renal iusufficiency, lupus activity, the use of broadspectrum antibiotics and prednisone. Conclusion LN may predispose to NI,the most common germ was eschefichia col.i, the second was klebsiella pneumonia and fungus. The factors related to NI were anemia, malnutrition, hypogananaglobulinemia, mass proteinuria, renal instufficiency, lupus activity, the use of broadspectrem antibiotics and prednisone.
出处
《医师进修杂志》
2005年第12期10-11,15,共3页
Journal of Postgraduates of Medicine
关键词
狼疮性肾炎
医院感染
细菌学
影响因素
Lupus nephritis
Nosocomial infection
Bacteriology
Influencing factors