期刊文献+

脑动脉狭窄相关性危险因素研究 被引量:6

Analysis of Risky Factors Related to Cerebral Artery Stenosis
在线阅读 下载PDF
导出
摘要 目的探讨脑动脉狭窄的分布特征及其相关性危险因素。方法101例缺血性脑卒中患者行数字减影脑血管造影术(DSA),并检测血脂、血糖、血纤维蛋白原,对脑动脉狭窄组与无狭窄组行对比分析。结果脑动脉狭窄组血清甘油三酯(TG)、载脂蛋白B(ApoB),纤维蛋白原(FIB)含量明显高于无动脉狭窄组(P<0.05),高密度脂蛋白明显低于无动脉狭窄组(P<0.05),动脉狭窄组中颈动脉狭窄率与ApoB含量呈正相关(r=0.426,P<0.05)。结论血中TG、ApoB、FIB高含量及高密度脂蛋低水平与脑动脉狭窄有关。 Objective To study feature of cerebral artery stenosis distribution and risky factors related to it. Methods DSA was performed, and blood lipid, blood glucose and fibfinogen (FIB) were determined in 101 patients with ischemie cerebrovascular diseases who were divided into both the cerebrovascular stenosis (CVS) and non-stenosis (CVNS) groups. Results The levels of triglyeride (TG), apolipoprotein B (Apo B), FIB in CVS group were significantly higher than that in CVNS group (P〈0.05), while the level of high density lipoprotein (HDL) in CVS groups was significantly lower than that in CVNS groups (P〈0.05). The level of Apo B was positively correlated to the rate of carotid artery stenosis (r=0.426, P〈0.05). Conclusion The results suggest that increase in blood TG, Apo B, FIB and decreas in blood HDL may play the roles in the pathogensiss of CVS.
出处 《中国临床神经外科杂志》 2005年第6期432-433,437,共3页 Chinese Journal of Clinical Neurosurgery
关键词 脑动脉狭窄 危险因素 缺血性脑卒中 脑血管造影 Cerebral artery stenosis Risky factors Iscbemie eerebrovaseular diseases DSA
  • 相关文献

参考文献9

二级参考文献58

  • 1朱汝锦.辛伐他汀的药理学及其对高胆固醇血症的治疗[J].国外医药(抗生素分册),1996,17(6):457-465. 被引量:3
  • 2陈新谦 金有豫.新编药物学[M](第14版)[M].北京:人民卫生出版社,1998.78.
  • 3Straznicky NE, Howes LG, Lam W, et al. Effects of pravastatin on cardiovascular reactivity to norepine phrine and angiotensin Ⅱ in patients with hypercholesterrolemia and systemic hypertension[J]. Am J Cardio, 1995,75:582
  • 4Treasure CB, Klein JL, Weintraub WS, et al. Benifical effects of cholesterol-lowering therapy on the coronary endothelium in patients with coronary artery disease [J]. NEJM, 1995,332(8):481
  • 5Andrews TC, Raby K, Barry J, et al. Effect of cholesterol reduction on myocardial is chemia in patients with coronary disease[J]. Circulation, 1997,95:324
  • 6Robert S, Rosenson, Christine C, et al. Antiatherrothrombotic properties of statins: Implications for cardiovascular event reduction[J]. JAMA, 1998, 279(20):1643
  • 7Corsini A, Raiteri M, Soma M, et al. Simvastatin but not pravastation inhibits the proliferation of rat aorta myocytes[J]. Pharm Res, 1991,23(2):173
  • 8Kempen HJM, Vemeer M, Dewit E, et al. Provastatins inhibit cholesterol ester accummulation in human monocyte-derived macrophages[J]. Arteropscler Thrpmb, 1991,11:146
  • 9Kimura M, Kurose I, Russell J, et al. Effects of fluvastatin on leukocyte-endothelial cell adhesion in hypercholesterolemia rats[J]. Arterioscler Thromb Vasc Biol, 1997,17:1521
  • 10王抒,中华医学检验杂志,1996年,19卷,339页

共引文献215

同被引文献77

引证文献6

二级引证文献24

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部