摘要
目的分析结肠黑变病的病因、镜下表现及防治措施.方法回顾性总结、分析30例结肠黑变病的临床表现、电子结肠镜检查、病理诊断资料.结果男6例,女24例,年龄18～81岁,平均50.6岁.镜下表现为:黏膜色素沉着,病变范围不等.病理检查见结肠黏膜固有层含色素颗粒的单核吞噬细胞沉积;6例伴发息肉,1例合并结肠癌,1例合并溃疡性结肠炎.结论结肠黑变病是良性可逆性疾病,在很大程度上与便秘,服用泻药有关,它能否导致结直肠肿瘤有待进一步研究.
Objective To analyze the pathogenesis endoscopic characteristic prevention and cure measures for melanosis coli. Methods 30 patients with melanosis coli was reviewed with clinical symptoms、electron endoscopy features and pathological characters. Results Male： female = 6：24, age from 18 to 81, average 50.6. Under colonoscope、the deposits of melanin could be found in the different areas of the lesions. The pathologic examination showed that the accumulation of mononuclear phagocytes, having pigment granules was contained in the layer of colonic mucosa, 6 cases have polype, and 1 case has colorectal carcinoma and 1 case has ulcerativecolitis. Conclusion Melanosis coli is a benign curable disease which is strongly related to the use of laxatives in the patients with constipation. Further study should be conducted to clarify the relationship between melanosis coli and colorectal neoplasm.
出处
《医药论坛杂志》
2005年第23期32-33,35,共3页
Journal of Medical Forum
关键词
结肠黑变病
内镜诊断
病因
泻药
Melanosis coli
Endoscopic diagnosis
Pathogeneisis
Laxative
