摘要
目的:对患者行颈动脉超声检查的同时调查动脉硬化的危险因素和患病年龄,并探讨二者之间的关系,以明确危险因子的存在和年龄增长对动脉硬化的影响。方法:选择2002-09/2004-12哈尔滨医科大学附属第一医院门诊及病房颈动脉超声检查患者300例,男183例,女117例;年龄40-89岁, 根据超声检查结果分为50%以上狭窄、有较明显斑块、内膜增厚和无明显异常4类。测量血压,检测血糖和血脂,并询问患者有无吸烟等病史。比较各种危险因子出现的比率,及危险因子、年龄增长与颈动脉硬化的关系。结果:300例患者全部进入结果分析。①超声所见动脉舁常与糖尿病的关系尤为密切,较之吸烟和高血压更有意义,其中54例伴有糖尿病的患者中超声所见异常占75%(41/54),153例吸烟的患者中颈动脉超声异常占64%(99/153),192例伴有高血压患者中超声所见异常占70% (135/192),P<0.05。②随着危险因子数的增加异常所见亦增加,有意义的异常所见增加只有从1项危险因子组到2项危险因子组[57% (110/192),65%(82/125),P<0.05]。③60-69岁组、70-79岁组斑块形成所占的比例增加明显[28%(24/86),46%(59/130),P<0.01]。结论:①危险因子中糖尿病和动脉硬化的关系最大。②随着危险因子数的增加和年龄的增长超声下动脉硬化的改变越明显。③对于高龄患者而言,年龄的增长比危险因子致动脉硬化更有意义。
AIM:To investigate risk factors and age of patients with arteriosclerosis, discuss the relationship between them while giving patients ultrasonic examination of carotid arteriosclerosis and explore the effects of risk factors and increase of age on arteriosclerosis. METHODS:A total of 300 patients with carotid artery ultrasnography from out-patient clinic and admission of the First Affiliated Hospital of Harbin Medical University from September 2002 to December 2004 were selected, including 183 males and 117 females,aged 40-89 years.They were divided into four kinds: over 50% constriction,obvious plaque, increased endometrium and no obvious abnormity.Patients were given examinations of blood pressure, blood glucose and blood lipids and inquired about smoking history.The appearing ratio of various risk factors and correlation of risk factors and increase of age with carotid artery arteriosclerosis were compared. RESULTS:AII 300 patients were involved in the result analysis① The ultrasound showed that the relation between abnormal artery and diabetes was close,and had more significance as compared with smoking and hypertension.Among 54 patients with diabetes there was 75% abnonnity showed in the ultrasound (41/54).Among the 153 patients who smoked there was 64% ultrasound abnormity in carotid artery (99/153). Among the 192 patients with hypertension there was 70% ultrasound abnormity (135/192) ,P 〈 0.05. ② With the increase of quantity of risk factors, abnormity increased also. The increase of the abnormality with significance only from 1 item to 2 items group of risk factors [57% (110/192),65% (82/125) ,P 〈 0.05].③The ratio of mottling formation increased significantly in _group of 60-70 year-old and .group of 70-80 year-old [28% (24/86), 46%(59/130) ,P 〈 0.01]. CONCLUSlON:① Diabetes mellitus is most related with arteriosclerosis among risk factors.② With increasing, of risk factors and age, the change of arteriosclerosis is more obviously by ultrasonic observation. ③ For senile patients the increase of age has more significance as compared with the risk factor-indueed arteriosclerosis.
出处
《中国临床康复》
CAS
CSCD
北大核心
2005年第41期34-36,共3页
Chinese Journal of Clinical Rehabilitation
作者简介
张亿倬,女,1972年生,黑龙江省哈尔滨市人,汉族,2005年哈尔滨医科大学毕业,博士,主治医师,主要从事腹部及外周血管超声诊断与治疗方面的研究.yzzhang01@hotmail.com