摘要
针对仔猪断奶腹泻(Post-weaningEscherichia colidiarrhea,PWECD)这一仔猪断奶后的常见病和多发病的病原特异性,阐述了利用K88和F18等特异性菌毛作为抗原免疫产蛋母鸡制备的抗PWECD特异性卵黄抗体对大肠埃希氏菌引起的断奶仔猪腹泻的作用机理。认为,特异性IgY用于防治PWECD,具有安全、高效、成本低、产率高、稳定性好,无药物残留,不会产生耐药性,符合现代动物管理理念等诸多优点,是一种能有效防治PWECD的绿色生物制剂,应用前景广阔。
The specific chicken-egg-yolk antibody（IgY） which was developed from laying hens immuned with K88 and F18 fimbriae, and the mechanism of the antibody against post weaing Escherichia coli diarrhea（PWECD） were expounded in the light of specificity of the causal agent leading to PWECD with a high rate of incidence. With being characterized by safety, high efficiency, low production cost, high yield, good stability, free antibiotic residues and no induction of antibiotic resistance, IgY was considered as a kind of green bio-preparation and would be applied widely in the future.
出处
《中国兽医科技》
CSCD
北大核心
2005年第10期832-836,共5页
Chinese Journal of Veterinary Science and Technology
基金
浙江省科技厅资助项目(2003C32002)
浙江省教育厅资助项目(20000240)
关键词
卵黄抗体
仔猪断奶腹泻
产肠毒素型大肠埃希氏菌
菌毛
egg-yolk antibody
post-weaning diarrhea in piglet
enterotoxigenic Escherichia coli
fimbriae
作者简介
由昭红（1979-），女，山东临清人，硕士生。
姜中其为通讯作者，研究方向为兽医药理学与毒理学，E-mail：zqjiang@zju．edu．cn
