摘要
目的:观察我国正常青年人群中前庭诱发肌源性电位(VEMP)出现的阳性率及各项参数指标.方法:选取52例(男31例,女21例)21~22岁正常健康人群,以短声为刺激声,单耳给声,同侧胸锁乳突肌(SCM)记录.结果:47例2耳均可引出VEMP,5例2耳均不能引出.总104耳中,94耳阳性,10耳阴性,阳性率90%.统计阳性耳各参数:p1潜伏期(15.97±3.22)ms、n2潜伏期(24.41±2.46)ms、p1n2间期(8.41±2.06)ms,幅值(33.27±14.37)μV,阈值(93.67±5.20)dB nHL. 统计47例正常人同一个体耳内差异的各参数为p1潜伏期(0.97±1.31)ms,n2潜伏期(1.23±1.30 )ms,p1n2间期(0.95±1.21 )ms,幅值(10.04±11.88)μV,阈值(2.29±2.56 )dB nHL.男女各参数比较差异无统计学意义.结论:绝大部分正常人可引出VEMP.VEMP的引出体现该侧耳球囊→前庭下神经→脑干前庭神经核→前庭脊髓通路→颈肌运动神经元这条反射途径的完整性.VEMP可能成为一种检测前庭终器及其传导通路完整性的方法.
Objective:To observe the positive rate and other variances of the vestibular evoked myogenic potentials (VEMP)in normal young people. Method: Fifty-two normal young people aged from 21-22 years old including 31males and 21 females were investigated. Intense clicks were given to one test ear and EMG was recorded from ipsilateral side. Resnlt:VEMPs were presented in both ears in 47 subiects, absent in either of the two ears in 5 subjects. Variances averaged from all 94 positive ears were as follows(mean± standard deviation) :latencies for pl (15.97±3.22)ms,latencies for n2 (24.41±2.46)ms, interval time between pl and n2 (8.41±2.06)ms,amplitude (33.27±14.37)μV,threshold (93.67±5.20)dB nHL. Inter-subject variances averaged from 47 normal subjects were as follows:latencies for pl (0.97±1.31)ms ,latencies for n2 (1.23±1.30)ms, interval time between pl and n2 (0.95±1.21)ms,amplitude (10.04±11.88)μV,threshold (2.29±2.56)dB nHL. There were no significant difference between males and females. Conclusion: VEMP can be recorded in most normal subjects. VEMP may travel along the hypothesized response pathway from the vestibular sacculus to the inferior vestibular nerve , vestibular nucleus, and lateral vestibulospinal tract to the SCM muscle. VEMP recording could become an attractive method for testing otolithic receptors and vestibulospinal pathways.
出处
《临床耳鼻咽喉科杂志》
CAS
CSCD
北大核心
2005年第22期1012-1014,共3页
Journal of Clinical Otorhinolaryngology
关键词
前庭诱发肌源性电位
声刺激
胸锁乳突肌
球囊
Vestibular evoked myogenic potentials I Acoustic stimulation
Sternocleidomastoid muscle
Saccule
作者简介
通讯作者:孔维佳(Email:wjkong@whuh.com)