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男性老年骨质疏松症患者血清IL-6、BGP和T含量变化及临床意义 被引量:2

Clinical Significance of the Changes of Serum Contents of IL-6,BGP and Testosterone in Aged Male Patients with Osteoporosis
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摘要 目的:探讨老年骨质疏松症患者血清白细胞介素-6(IL-6)、骨钙素(BGP)和睾酮(T)含量的变化及临床意义。方法:应用放射免疫分析对46例老年骨质疏松症患者进行了血清IL-6、BGP和T水平测定,并与35名正常健康人作比较。结果:老年骨质疏松症患者血清IL-6水平明显高于正常健康人(P<0.01),而BGP、T水平明显低于正常人(P<0.01)。结论:测定老年骨质疏松症患者血清中IL-6、BGP和T水平为临床诊断治疗提供了一个有价值的数据。 Objective To explore the clinical significance of changes of serum contents of IL -6, bone glaprotein (BGP) and testosterone (T) in aged male patients with osteoporosis. Methods Serum IL -6, BGP and T levels were determined with RIA in 46 aged male patients with osteoporosis and 35 controls. Results The serum levels of IL -6 were significantly higher but levels of BGP, T were significantly lower aged male patients with osteoporosis than those in controls ( P 〈0.01 ). Conclusion Through measurement of serum IL -6, BGP and T levels in these patients, valuable data were obtained, which in turn would provide guidelines for diagnosis and treatment.
出处 《放射免疫学杂志》 CAS 2005年第5期339-341,共3页 Journal of Radioimmanology
关键词 老年骨质疏松 白细胞介素-6 骨钙素 睾酮 老年骨质疏松症 血清IL-6 临床意义 含量变化 BGP 患者 血清白细胞介素 水平测定 正常健康人 aged osteoporosis, interleukin - 6 ( IL - 6 ) , bone glaprotein (BGP) , testosterone (T)
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参考文献5

  • 1罗南萍,杨道理,赵玉堂,彭立义,刘桂香.骨代谢指标与老年男性骨质疏松症关系的研究[J].中华核医学杂志,2001,21(4):223-224. 被引量:14
  • 2中国人原发性骨质疏松症诊断标准(试行)[J].中国骨质疏松杂志,1999,5(F03):1-3. 被引量:325
  • 3Ralston SH. Analysis of gene expression in bone biopsies by polymerase chain reation reaction: evidence fenhanced cytokine expression in postmenopausal osteoporosis. J Bone Miner Res. 1994,9(6):883.
  • 4Kawaguchi H, Nemoto K, Raisz LG, et al. Interleukin-4 inhibits prostagland in G/H. Synthase-2 and Cytosolic phospholipase A2 induction. J Bone Miner Res. 1996, 11(3):358.
  • 5Miyaura C, Kosanok, Mosozawa T, et al. Endogenous bone-nesorbing. Factors in estrogen deficiency cooperative effects of IL-1 and IL-6. J Bone Miner Res. 1995, 10(9):1365.

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  • 1徐苓.骨质疏松症的流行病学[J].中国骨质疏松杂志,1996,2(1):56-59. 被引量:11
  • 2李梅.老年慢性支气管哮喘患者血清TNF-α、IL-6水平及其临床意义[J].放射免疫学杂志,2005,18(6):440-441. 被引量:18
  • 3陈雨振.脑梗死患者血清IL-6水平的变化[J].放射免疫学杂志,2006,19(2):83-84. 被引量:9
  • 4Kishikawa H,Shimokama T,Watanabe T.Localization of T lymphocytes and macrophages expressing IL-1,IL-2 receptor,IL-6and TNF in human aortic intima.Role of cell-mediated immunity in human atherogensis[J].Virchows Arch Pathol Anat Histopathol,1993,45(4):423-425
  • 5Blay JY,Negrier M,Combaret V,et al.Serum Levels of interleukin-6 as a prognosis factor in matastatic renal cell carcimoma[J].Cancer Res,1992,52(2):3317-3318.
  • 6Carey AL,Lamont B,Andrkopoulos S,et al.Interleukin-6 gene expression is increased in insulin resistomt rat skeletal muscle following insulin stimulation[J].Biochem Biophys Res Commun,2003,170(5):302-305.
  • 7Ndre-Schmutz I,Hindelang C,Bencist C,et al.Cellular and molecular changes accompanying the progression from insulitios to diabetes[J].Eur J Immunol,1999,29(3):245-247.
  • 8Ralston SH.Analysis of gene expression is bone biopsies by polymerase chain reation reaction:evidence fenhanced cytokine expression in postmenopausal osteoporosis[J].J Bone Miner Res,1994,9(6):883.
  • 9Schomin M,Eisenhardt A,Ritz E.Microinflammatory state of uremia[J].Blood Purif,2000,18(4):327.
  • 10Nisbeth N,Hallgren R,Eriksson O,et al.Endotoxemid in chronic renal failure[J].Nephron,1987,45(2):93-94.

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