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米非司酮配伍米索前列醇用于稽留流产45例

Association of mifepristone with misoprostol in 45 cases of missed abortion
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摘要 目的观察米非司酮配伍米索前列醇在稽留流产中的疗效。方法对45例稽留流产患者应用米非司酮配伍米索前列醇治疗。头2 d内分次口服米非司酮150 mg(50、25、50、25 mg,每次间隔12 h),第3 d口服米索前列醇600μg。必要时4-6 h后加服米索前列醇200μg。结果完全流产率达91.11%,患者清宫率及阴道出血量明显减少。结论米非司酮配伍米索前列醇用于稽留流产完全流产率高,不良反应小。 Objective To observe the therapeutic effects of use in association of mifepristone with misoprostol in the patients of missed abortion. Methods The 45 cases of missed abortion were treated with association of mifepristone with misoprostol. First and second day, mifepfistone(150mg,p, o, ) were administered (50、25、50 and 25 mg, respectively, eyery other 12 h),third day misoprostol (600μg, p. o. ) were administered, If need ,4 -6h late, added misoprostol(200μg, p. o, ). Results The rate of complete abortion was 91.11% ,the rate of cleaning uterus and content of bleeding in vagina both were were significantly decreased in the Patients. Conclusion Use in association of mifepristone with misoprostol can significantly increase the rate of complete abortion and decrease adverse reactions in patients of missed abortion.
作者 林晓茵
出处 《广东药学》 2005年第5期39-40,共2页 Guangdong Pharmaceutical Journal
关键词 米非司酮 米索前列醇 稽留流产 mifepristone misoprostol missed abortion
作者简介 林晓茵(1977-),女,本科,助理讲师,从事药理学教学工作.
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