摘要
目的回顾、反思20世纪肿瘤外科的发展、成就,探讨21世纪肿瘤外科研究的目标和任务。方法通过3000多例胸腹部癌术后患者的随访及40多年临床实践病例的回顾、分析、评价及自我反思,总结临床实践正反两方面的经验与教训,提出几点新思维、新认识。结果随访发现:①术后复发、转移是影响手术远期疗效的关键因素。研究防治癌症术后复发、转移的方法才是提高手术远期疗效的关键。外科医师必须重视及研究术后复发、转移的防治措施。②必须进行复发、转移的实验基础研究,若无基础研究的突破,则临床疗效很难提高。结论肿瘤外科下一个研究目标应该是根治术后抗复发、抗转移的实验研究和临床研究,以进一步提高术后远期疗效抗复发是手术治癌疗效的关键,抗转移是癌症治疗的核心问题。
Objective To review and reflect the development and achievement in surgical therapy for cancer in 20th century, and to inquire and foresee the objectives and tasks of the study on tumor surgery in 21st century. Methods Based on the data of a long term follow-up survey of more than 3000 cancer patients who had undertaken thoracic or abdominal operations, and also on a review, analysis, evaluation and reflection of clinical cases accumulated for 40 years, clinical experiences of both positive and negative aspects were summed up, a few new personal ideas and knowledge were raised. Results It was found that： （1） Postoperative recurrence and metastases played as the key factors which affected the curative effect. Therefore therapies and procedures to control postoperative recurrence and metastases are vital in improving the curative effect. （2） Improvement on curative effect of cancer surgery can be hardly expected if no breakthrough in basic researches is made. Conclusion Experimental and clinical researches should be aimed at the radical cure of postoperative recurrence and metastases, so as to improve the surgical treatment of malignancies in the future.
出处
《解放军医学杂志》
CAS
CSCD
北大核心
2005年第9期762-764,共3页
Medical Journal of Chinese People's Liberation Army
关键词
肿瘤外科
肿瘤转移
复发
surgery of cancer
neoplasm metastasis
recurrence
作者简介
徐泽，1933年10月出生，湖北中医学院附属医院外科主任，教授，主任医师，博士研究生导师，实验外科研究所所长。兼任中华医学会武汉分会常务理事，武汉微循环学会副理事长，国际肝病协作交流中心学术委员，国际外科医师联会会员，中华实验外科杂志、腹部外科杂志常务编委，享受国务院政府特殊津贴。从事外科工作40多年，开展实验外科工作15年，“自制Z-CI型腹腔-静脉转流装置治疗肝硬化顽固性腹水的实验研究和临床应用”获省政府科技成果二等奖，在全国12个省市38家医院推广应用；“用实验外科方法探讨肺日本血吸虫病病理生理、发病机理的实验研究”获国家科技进步二等奖。参与编写《肝病治疗学》等6部专著，发表论文106篇。1987年开始建立肿瘤动物模型及转移、复发动物模型，寻找抑制肿瘤转移的方法。2001年出版专著《癌症治疗新认识和新模式》。
