摘要
用一种改进的高效液相色谱方法测定了具有高毒性药酒中乌头碱的含量,基于测定结果确定了该药酒的中毒剂量.同时揭示了该酒剂乌头碱中毒的化学原因.
A modified HPLC method was used for the separation and the determination of aconitum alkaloids in medicine wine. The toxieal dosages of the preparations were established on the basis of the data from the above determination. At the same time, the chemical reasons of aeonitine poisoning were revealed. These reasons have provided some scientific bases for the clinical safe drug use.
出处
《吉林大学学报(理学版)》
CAS
CSCD
北大核心
2005年第5期677-679,共3页
Journal of Jilin University:Science Edition
基金
国家自然科学基金(批准号:39870874)
关键词
乌头碱
中毒剂量
高效液相色谱法
aconitine
toxication dosage
high performance liquid chromatograph method
作者简介
张宏桂(1955~),男,汉族,博士研究生,教授,从事光谱分析化学研究,E-mail:zhanghg4@163.com.
联系人:张寒琦(1948~),男,汉族,博士,教授,博士生导师。从事光谱化学分析研究,E-mail:analchem@mall.jlu.edu.cn