摘要
目的探讨新辅助化疗联合乳腔镜保乳手术近期疗效及美容效果.方法64例乳腺癌接受CEFi方案化疗2～4周期后行乳腔镜保乳术.结果CEFi方案新辅助化疗CR 5例,PR 52例,SD 5例客观有效率92.0%(57/62),病理学完全缓解率6.5%(4/62),保乳手术后对乳腺形态满意率98.4%(63/64).随访2～30个月,平均18个月,未发现局部复发.结论早期乳腺癌新辅助化疗,肿物降低分期,便于保乳治疗.乳腔镜保乳并发症少,乳腺形态变化小,美观效果好.
Objective To evaluate short-term effects and cosmetic results of neoadjuvant chemotherapy combined with mammary ductoscopy in breast-conserving surgery. Methods After a neoadjuvant chemotherapy with CEFi regimen for 2-4 cycles, the breast-conserving surgery was performed by using mammary ductoscopy in 64 cases. Results Responses to the neoadjuvant chemotherapy with CEFi regimen showed a complete remission （CR） in 5 cases, a partial remission （PR） in 52 cases, and a stable disease （SD） in 5 cases, the effective rate being 92.0% （57/62）. Pathological examination revealed a CR rate of 6.5% （4/62）. The cosmesis was favorable in 98.4% of cases （63/64）. Follow-up examinations for 2-30 months （mean, 18 months） found no local recurrence. Conclusions Neoajuvant chemotherapy of early breast cancer decreases the odds of progression of disease and benefits further breast-conserving surgery. Application of mammary ductoscopy in breast-conserving surgery has advantages of little complications and satisfactory cosmetic outcomes.
出处
《中国微创外科杂志》
CSCD
2005年第9期748-749,共2页
Chinese Journal of Minimally Invasive Surgery
关键词
乳腺癌
新辅助化疗
乳腔镜
保乳手术
Breast cancer
Neoadjuvant chemotherapy
Mammary ductoscopy
Breast-conserving surgery
