摘要
目的了解脂肪酶在急性胰腺炎诊断中的作用,同时探讨淀粉酶和脂肪酶联合检测诊断急性胰腺炎的价值。方法采用动力学法和水解消浊分别对61例急性胰腺炎患者、64例非急性胰腺炎患者和120例健康体检者测定血淀粉酶、血脂肪酶,比较其对诊断胰腺炎的敏感性、特异性及准确度。结果淀粉酶对急性胰腺炎诊断的敏感度、特异度和准确度分别是80.3%,82.8%,81.6%,脂肪酶对急性胰腺炎诊断的敏感度、特异度、准确度分别是88.5%,87.5%,88%,淀粉酶和脂肪酶联合诊断急性胰腺炎的敏感度、特异度、准确度分别是100%,92.6%,96%。结论脂肪酶可用于急性胰腺炎的诊断,联合检测脂肪酶和淀粉酶可以快速诊断急性胰腺炎和有效预测病情,指导临床治疗。
Objective To investigate the clinical significance of detecting serum lipase on diagnosis of acute pancreatitis, and elevate the effect of serum lipase detection combined with amylase in diagnosis of patients with acute pancreatitis (AP). Methods In 61 cases of AP patients, 64 cases of non AP patients, 120 cases of healthy volunteers, serum amylase, serum lipase were detected respectively. Moreover, the sensitivity, specificity and preciseness of two substances to acute pancreatitis were compared. Results The sensitivity, specificity and preciseness of serum amylase to acute pancreatitis was 80.3 %, 82.8 %, 81.6%. The sensitivity, specificity and preciseness of serum lipase to acute pancreatitis was 88.5 %, 87.5 %, 88 %, the sensitivity,specificity and preciseness of serum lipase combine with serum amylase to acute pancreatitis were 100 %, 92.6 %, 96 %. Conclusions It is useful to detect serum lipase in dlagn^c~is of acute pancreatitis. Moreover, detection of serum lipase associated with serum amylase have more values in rapid diagnosis and efficient prognosis of patients with acute pancreatitis.
出处
《实用全科医学》
2005年第6期555-556,共2页
Applied Journal Of General Practice