摘要
目的:观察复方角菜酸脂栓在痔上黏膜环切除(PPH)术后应用的疗效。方法:116例痔病PPH术后病人,分为2组。试验组予复方角菜酸脂栓,对照组予醋酸氯已定痔疮栓,均于术后即刻塞肛1枚,术后d1起每日2次,每次1枚,早晨便后及晚上睡前给药。于用药d2和d7,经肛门镜检查,对其创面水肿、出血、肛门疼痛等作出评估。结果:术后d2试验组疼痛总有效率为97%,对照组为58%,2组疼痛疗效有非常显著差异(P<0.01)。术后d2和d7水肿总有效率试验组为92%和98%,对照组为51%和71%,2组水肿疗效有非常显著差异(P<0.01)。2组术后d2及d7对出血疗效无显著差异(P>0.05)。结论:复方角菜酸脂栓能有效改善痔病病人PPH术后疼痛和水肿等局部症状。
AIM： To observe the effect of compound carraghenates suppositories after the procedure for prolapse and hemorrhoids （PPH）. METHODS ： One hundred and sixteen patients with hemorrhoids were divided into two groups. The patients in the trial group were given compound carraghenates suppositories via rectum and the patients in the control group were given chlorhexidine acetate suppositories via rectum just after the procedure, twice a day beginning from d 1 after PPH. The symptom of edema, bleeding and pain were observed at d 2 and d 7 after the treatment. RESULTS： The total effective rates for pain were 97 % in the trial group and 58 % in the control group at d 2 after PPH with significant difference （P 〈 0.01 ）. The total effective rates for edema were 92 % and 98 % in trial group, 51% and 71% in control group at d 2 and d 7 after PPH（P 〈0.01 ）. But the total effective rates for bleeding of the two groups had no significant difference （ P 〉 0.05 ）. CONCLUSION ： Compound carraghenates suppositories possess significant effect in edema and pain after PPH.
出处
《中国新药与临床杂志》
CAS
CSCD
北大核心
2005年第9期690-692,共3页
Chinese Journal of New Drugs and Clinical Remedies
关键词
痔
栓剂
投药
直肠
hemorrhoids
suppositories
administration, rectal
作者简介
黄城鑫（1962-），男，浙江萧山人，主治医师，主要从事肛肠外科工作。[联系人]黄城鑫。Phn：86-571-8201．1619。E-mail：hcx301@126．com
