摘要
目的通过对12例艾滋病(AIDS)合并马尔尼菲青霉病(PSM)临床资料的分析,提高对该病的认识。方法回顾分析2002年11月至2003年11月收治的12例AIDS合并PSM的住院患者的资料。PSM的确诊依靠培养和病理检查。结果本组患者以反复发热、咳嗽、消瘦、腹泻、贫血、淋巴结肿大,皮肤损害尤其是皮肤坏死性丘疹为临床特点,外周血CD4计数均少于0.1×109/L。结论遇上述情况时应考虑PSM并行相关检查,此对PSM的早期诊断、早期治疗和改善预后有重要意义。本组1例极可能是江西首次发现的AIDS合并PSM。
Objective To improve the degree of acquaintance to AIDS associated Pencilliosis marneffei （PSM）. Methods Review and analyze the clinical characteristics and treatment of twelve cases of AIDS-associated PSM hospitalized from November 2002 to November 2003. PSM was diagnosed by culture separation and pathological examination. Results Most of the patients presented with prolonged fever, cough, weight loss. diarrhea, anemia, lymphadenopathy and skin lesions, especially necrotic papular eruptions. All patients had significantly decreased peripheral blood CD4 lymphocyte counts （less than 0. 1 × 10^9/L）. Conclusions Clinical doctors should consider the possibility of PSM when the sufferers have the mentioned symptoms. Culture and pathological examination should be taken as soon as possible. It is important for the successful management and treatment of AIDS -associated PSM to diagnose rapidly and accurately. One of the cases may be the first case of PSM associated with AIDS in Jiangxi Province.
出处
《中华传染病杂志》
CAS
CSCD
北大核心
2005年第3期195-198,共4页
Chinese Journal of Infectious Diseases
基金
广州市重大科技攻关项目(2001-Z-023-01)
作者简介
唐小平，Email：xtang@21cn．com
