摘要
目的探讨影响新生儿破伤风(NT)发生的因素及其相互间的关系,为制定有效干预措施提供科学依据。方法采用匹配病例对照研究设计,用条件logistic回归分析和通径分析方法,探讨直接和间接影响NT发生的因素及其之间的相互关系。结果多因素条件logistic回归分析结果显示,接生过程的消毒、家庭年人均收入、婴儿性别和胎次的OR值分别为0.002、0.001、101.442、4.891(P<0.01)。通径分析显示,接生过程的消毒、婴儿性别和脐带残端包裹为直接影响NT发生的主要因素,其通径系数分别为0.532、0.212、0.212,分别占总直接影响的42.765%、17.039%、17.039%;母亲文化程度、分娩地点、接生员培训为间接影响NT发生的主要因素,其通径系数分别为-0.134、-0.272、-0.326,分别占总间接影响的15.107%、30.665%、36.753%。结论为了消除NT不仅要严格实施接生过程的消毒,而且要针对间接影响因素采取必要的健康教育和行为干预措施。
Objective To identify risk factos for neonatal tetanus （NT）to provide scientific evidence for developing an effective strategy against NT. Methods A matched case-control study was conducted with conditional logistic regression medel and path analysis to analyze both direct and indirect risk factors associated with NT. Results Odds ratio （OR） for NT was 0.002,0.001,101.442, and 4. 891 of disinfection in delivery, average annual family income per person, gender of baby and parity, respectively, （P〈0.05）by multivariate conditional logistic regression analysis. Disinfection in delivery, baby gender and umbilical cord wrapping with dressing were main risk factors according to path analysis with coefficients of 0. 532,0. 212 and 0.212 respectively, accounting for 42. 765 %, 17. 039 % and 17.039 % of the total factors, respectively. Mother＇s education, delivery location and training for midwives were indirect risk factors with coefficients of - 0. 134, - 0.272 and - 0. 326, respectively, accounting for 15. 107%, 30.665 %, and 36.753%, respectively. Conclusion It is important to strength disinfection in delivery and make efforts on health education and behavioral intervention against indirect risk factors for NT.
出处
《中国计划免疫》
2005年第4期282-284,共3页
Chinese Journal of Vaccines and Immunization
作者简介
于兰（1961-），女，天津市人，中国疾病预防控制中心性病艾滋病预防控制中心讲师，硕士，从事疾病预防控制工作。
