摘要
目的 探讨屈窝软组织肉瘤的治疗及预后。方法 53例屈窝软组织肉瘤, 52例手术,其中4例以皮瓣覆盖血管、神经及修复皮肤缺损,放疗30例,化疗33例。结果 伤口并发症8例,复发19例,转移21例,死亡22例。放疗、初治患者局部控制率明显优于未放疗、转诊患者,肿瘤大小及组织学级别与预后相关。结论 放疗可以提高屈窝软组织肉瘤局部控制率,肿瘤大小及组织学级别在其预后判断上有价值,使用皮瓣可以提高屈窝软组织肉瘤保肢率,减少并发症。
Objective To explore the treatment and prognosis of soft tissue sarcomas in flexor fossae. Methods 52 of 53 patients with soft tissue sarcomas in flexor fossae were treated surgically; four of them were reconstructed by transposition flap to cover the main blood vessels and nerves. Radiotherapy delivered in 30 patients and chemotherapy in 33 patients. Results Wound complications occurred in 8 patients, recurrence in 19, metastasis in 21 and death in 22. The patients who received radiotherapy had a significantly better local control rate than those did not received radiotherapy or were treated by prior surgery. The size and histological grade of tumors are related with prognosis. Conclusion Radiotherapy is effective in local control of soft tissue sarcomas in flexor fossae, tumor size and histological grade play roles in assessment of prognosis, application of transposition flap could enhance the rate of limb saving and reduce complication in patients with soft tissue sarcomas.
出处
《中国骨肿瘤骨病》
2005年第2期65-67,共3页
Chinse Journal Of Bone Tumor And Bone Disease