摘要
目的:研究冻融胚胎移植的临床应用及分析影响冻融胚胎移植妊娠率的相关因素.方法:对63例80个冻融胚胎移植周期进行回顾性分析,通过IVF或ICSI获得的剩余胚胎采用慢速法冷冻保存,快速法解冻复苏.结果:解冻392个胚胎,成活269个胚胎,胚胎复苏率为68.62%.周期临床妊娠率为23.75%.每周期植入3个胚胎组的临床妊娠率显著高于植入≤2个胚胎组(χ2=4.98,P<0.05).妊娠周期胚胎细胞完整率及优质胚胎率显著高于非妊娠周期(67.28%vs60.09%,89.09%vs73.55%,均为P<0.025).结论:冻融胚胎移植的成功率与移植胚胎的数量和质量密切相关.
AIM： To study the clinical application of transferring frozen-hawed embryos and to analyze the factors influencing the outcome of frozen-thawed embryos transfer （FET）. METHODS： Eighty FET cycles in 63 cases from September 2003 to December 2004 were analyzed retrospectively. The suppernumberary embryos obtained from in vitro fertilization （IVF） or intracytoplasmic sperm injection （ICSI） were cryopreserved by slow freezing and rapid thawing method. RESULTS： Two hundred and sixty-nine out of the 392 thawed embryos survived, with an embryo survival rate of 68.62%. The pregnancy rate was 23.75% per FET cycle. The pregnancy rate was significantly higher in the group of transferring 3 embryos than that of transferring ≤2 embryos（30.91 % vs 8%, P 〈0.05）. There was significant difference between the conceived and nonconceived cycles in term of the rate of cleavage integrality and the percentage of quality embryos （67.28% vs 60.09%, 89.09% vs 73.55%, respectively P 〈0.025）. CONCLUSIONS： The number and quality of frozen-thawed embryos transferred are the most important factors influencing the pregnancy rate after frozen-hawed embryo transfer.
出处
《第四军医大学学报》
北大核心
2005年第16期1503-1505,共3页
Journal of the Fourth Military Medical University
关键词
冻融
冷冻胚胎
胚胎移植
妊娠率
frozen-thawed
embryo cryopreservation
embryo transfer
pregnancy rate
作者简介
王晓红（1968-），女（蒙古族），河南省新蔡县人．主治医师，讲师，博士生（导师姚元庆），Tel．（029）83377711 Email．tdhivf@fmmu．edu．cn
