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熊去氧胆酸治疗慢性乙型肝炎患者γ-谷氨酰转肽酶升高的疗效观察 被引量:1

Effects of ursodeoxycholic acid on lowering GGT in patents with chronic hepatitis B virus
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摘要 目的 探讨熊去氧胆酸治疗慢性乙型肝炎患者持续性γ-谷氨酰转肽酶(GGT)升高的疗效.方法 69例患者随机分为治疗组(35例)和对照组(34例),治疗组予以常规保肝治疗和熊去氧胆酸(UDCA)口服,对照组单独予以常规保肝治疗.分别检测两组治疗15 d和30 d时GGT的水平.结果 对照组和治疗组在治疗15 d和30 d时GGT值比较差异均有统计学意义(P<0.05).结论 熊去氧胆酸能快速、有效地降低慢性乙型肝炎患者持续升高的GGT. Objective To investigate the effects of ursodeoxycholic acid on lowering continuously elevated gamma glutamyl transpeptidase(GGT) levels in patients suffering from chronic hepatitis B virus.Methods Patients in the treatment group were given conventional liver protecting treatment in combination with oral ursodeoxycholic acid therapy, in a dose of 250 mg twice a day.And patients in control group were given conventional liver protecting treatment.The GGT levels were detected on the 15th day and 30th day after treatment.Results There were significant differences of GGT levels between the treatment group and control group on the 15th day and 30th day affer therapy (P<0.05).Conclusions Ursodeoxycholic acid can lower the continuously elevated GGT levels in patients with chronic hepatitis B virus quickly and effectively.
出处 《中国实用医刊》 2010年第9期36-36,38,共2页 Chinese Journal of Practical Medicine
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