摘要
从动物实验角度研究了外源性谷胱甘肽（ＧＳＨ）对汞分布的影响。结果表明：染汞同时投入ＧＳＨ后，甲状腺、肝汞浓度与单纯染汞组比较各剂量组均减小，且有显著差异。肾汞低、中剂量组投ＧＳＨ后肾汞含量下降，其中低剂量组下降明显。提示，外源性ＧＳＨ可降低组织中汞含量，对汞中毒防治有重要理论及实践意义。
he study was focused on the effect of
exogenous glutathione(GSH)on the distribution of mercuryfrom the
point of view of animal experiment. The results showed that when GSH
was administered atthe same time of mercury exposure, the
concentration of mercury in thyroid and liver decrease in eachgroup
of different dose compared with the simple mercury exposure group
significantly. After GSH wasadministered, the content of mercury in
kidney decrease in low and middle dose group, especially in thelow
dose group. All the results indicated that exogenous glutathione
could decrease the content of mer-cury in tissues. It is of great
theoretical and practical significance in prevention and cure of
mercury poi-son.
出处
《中国医科大学学报》
CAS
CSCD
1995年第6期566-568,共3页
Journal of China Medical University
基金
国家自然科学基金资助课题
