摘要
对海马水提取物（ＷＥＨ）和乙醇提取物（ＥＥＨ）中氨基酸和微量元素含量进行了分析比较，测得两提取物中含有多种氨基酸和Ｆｅ，Ｚｎ，Ｃｕ，Ｍｎ等元素。两提取物（５００，１０００ｍｇ／ｋｇ，ｉｐ）能增加正常小鼠和免疫受抑小鼠脾重，提高碳粒廓清率和吞噬指数，提高外周血液淋巴细胞ＡＮＡＥ阳性百分率，促进血清溶血素抗体的生成。体外实验可提高小鼠脾淋巴细胞增殖，其量效关系呈双向变化。结果表明，海马提取物具有促进小鼠免疫功能的作用。此外两提取物（５００，１０００ｍｇ／ｋｇ，ｉｇ）对小鼠血清ＭＤＡ含量和游泳持续时间无明显影响。
The amion acids and trace elements in the water extract of hippocampus(WEH) and ethanol extract of hippocampus(EEH)have analysised in this paper.The results showed that WEH and EEH contain several kinds of amino acid and Fe,Mn,Zn, Cu etc trace elements. Both extracts(500,1000mg/kg,ip)increase spleen weight,ANAE rate of percent of lymphocytes in the peripheral blood,carbon granular clearance and phagocytic index,serum hemolysin production in mice. They can promste spleen lymphocyte proliferation in vitro. But both extracts(500,1000mg/kg,ig)have on significant effects on MDA cotent in serum and swimming sustained in mice.
出处
《潍坊医学院学报》
1995年第2期105-109,共5页
Acta Academiae Medicinae Weifang
关键词
海马提取物
微量元素
免疫
丙二醛
药理
extracts of hippocampus
trace element
immune enhancement/regulation
MDA
