摘要
本文用斑点分子杂交法检测了无症状HBsAg携带者和乙型肝炎病人尿中HBV DNA,阳性率分别为12.0％及13.3％、血清HBeAg阳性的无症状HBsAg携带者和乙型肝炎病人尿中HBV DNA的阳性率可达21.1％及28.6％。HBV活性在尿液或尿便混合中可存在一定时间.本文认为,尿在乙型肝炎的接触传播中,可能起一定作用.
HBV DNA in urine from asymptomatic HBsAg carriers and hepatitis B patients was examined with a simple spot hybridization technique. The results showed that the positive rates of HBV DNA in urine from asymptomatic carriers and hepatitis B patients were 12.0% (12/100) and 13.3% ( 4/30 ) respectively, and those of HBV DNA in urine from asymptomatic HBsAg carriers and hepatitis B patients with positive HBeAg in serum were 21.1 % ( 8/38 ) and 28.6% ( 4/14 ) respectively. The results showed that after the samples ( urine or mixture of urine and faeces ) were stored for 7-10 days at 25 or 37 ℃, there was still HBV DNA in them. So we consider that urine may serve as a factor of transmission and play a role in the contact infection of hepatitis B virus.
出处
《第一军医大学学报》
CSCD
1989年第2期119-121,共3页
Journal of First Military Medical University
关键词
乙型肝炎
尿
传播途径
hepatitis B
route of transmission
urine
HBV DNA
HBsAg
